Evidence map›Paper›PMID 27785153›Full record

ArticleBioData mining2016

Developing a modular architecture for creation of rule-based clinical diagnostic criteria.

Na Hong, Jyotishman Pathak, Christopher G Chute, Guoqian Jiang

Abstract read
In one paragraph

Article in BioData mining, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Na HongDepartment of Health Sciences Research, Mayo Clinic, 200 First Street, SW, Rochester, MN 55905 USA ; Institute of Medical Information, Chinese Academy of Medical Sciences, Beijing, China.
Jyotishman PathakWeill Cornell Medical College, Cornell University, New York, NY USA.
Christopher G ChuteSchool of Medicine, Johns Hopkins University, Baltimore, MD USA.
Guoqian JiangDepartment of Health Sciences Research, Mayo Clinic, 200 First Street, SW, Rochester, MN 55905 USA.ORCID 0000-0003-2940-0019

Funding

Institute for Clinical and Translational ResearchUL1TR001079 · NCATS · JOHNS HOPKINS UNIVERSITY · PI FORD, DANIEL ERNEST · 2013 to 2017
$60.1M
National Infrastructure for Standardized and Portable EHR Phenotyping AlgorithmsR01GM105688 · NIGMS · WEILL MEDICAL COLL OF CORNELL UNIV · PI LUO, YUAN, PATHAK, JYOTISHMAN · 2013 to 2020
$5.7M
Informatics Tools for Pharmacogenomic Discovery using Practice-based DataR01GM103859 · NIGMS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI DENNY, JOSHUA C., PATHAK, JYOTISHMAN · 2014 to 2017
$2.4M
Modeling Social Behavior for Healthcare Utilization in DepressionR01MH105384 · NIMH · WEILL MEDICAL COLL OF CORNELL UNIV · PI PATHAK, JYOTISHMAN, SHETH, AMIT P · 2015 to 2018
$2.1M
caCDE-QA: A Quality Assurance Platform for Cancer Study Common Data ElementsU01CA180940 · NCI · MAYO CLINIC ROCHESTER · PI JIANG, GUOQIAN · 2014 to 2016
$1.1M
NCATS NIH HHS UL1 TR001079NCI NIH HHS U01 CA180940NIGMS NIH HHS R01 GM103859NIGMS NIH HHS R01 GM105688
6 · The paper itself

Abstract

backgroundWith recent advances in computerized patient records system, there is an urgent need for producing computable and standards-based clinical diagnostic criteria. Notably, constructing rule-based clinical diagnosis criteria has become one of the goals in the International Classification of Diseases (ICD)-11 revision. However, few studies have been done in building a unified architecture to support the need for diagnostic criteria computerization. In this study, we present a modular architecture for enabling the creation of rule-based clinical diagnostic criteria leveraging Semantic Web technologies. METHODS AND

resultsThe architecture consists of two modules: an authoring module that utilizes a standards-based information model and a translation module that leverages Semantic Web Rule Language (SWRL). In a prototype implementation, we created a diagnostic criteria upper ontology (DCUO) that integrates ICD-11 content model with the Quality Data Model (QDM). Using the DCUO, we developed a transformation tool that converts QDM-based diagnostic criteria into Semantic Web Rule Language (SWRL) representation. We evaluated the domain coverage of the upper ontology model using randomly selected diagnostic criteria from broad domains (n = 20). We also tested the transformation algorithms using 6 QDM templates for ontology population and 15 QDM-based criteria data for rule generation. As the results, the first draft of DCUO contains 14 root classes, 21 subclasses, 6 object properties and 1 data property. Investigation Findings, and Signs and Symptoms are the two most commonly used element types. All 6 HQMF templates are successfully parsed and populated into their corresponding domain specific ontologies and 14 rules (93.3 %) passed the rule validation.

conclusionOur efforts in developing and prototyping a modular architecture provide useful insight into how to build a scalable solution to support diagnostic criteria representation and computerization.

Indexed as

Diagnostic CriteriaICD-11OntologyQDMSWRL

Identifiers

PMID27785153
PMCPMC5073928

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.