ArticleNeuropsychiatric disease and treatment2016
Personality features, dissociation, self-stigma, hope, and the complex treatment of depressive disorder.
Article in Neuropsychiatric disease and treatment, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 3 of them syntheses that pooled it.
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Who cites it
10 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Co-occurrence of dissociation and anxiety and depressive disorders in adults: a scoping review.Frontiers in psychiatry · 2026Pooled it
- Self-stigma in Serious Mental Illness: A Systematic Review of Frequency, Correlates, and Consequences.Schizophrenia bulletin · 2021Pooled it
- Selection and measurement of control antidepressants in clinical tests for Chinese: A systematic review.Medicine · 2017Pooled it
- Looking through the lens of stigma: Understanding and anticipating concerns about the responsible development and use of psychiatric electroceutical interventions (PEIs).SSM. Mental health · 2023Article
- Early Maladaptive Schemas and Self-Stigma in People with Physical Disabilities: The Role of Self-Compassion and Psychological Flexibility.International journal of environmental research and public health · 2022Article
- Internalized-stigma and dissociative experiences in bipolar disorder.Frontiers in psychiatry · 2022Article
- Self-Stigma and Treatment Effectiveness in Patients with SSRI Non-Responsive Obsessive-Compulsive Disorder.Psychology research and behavior management · 2021Article
- Self-stigma and treatment effectiveness in patients with anxiety disorders - a mediation analysis.Neuropsychiatric disease and treatment · 2018Article
- Comparison of self-stigma and quality of life in patients with depressive disorders and schizophrenia spectrum disorders - a cross-sectional study.Neuropsychiatric disease and treatment · 2016Article
- Association between operational positive depression symptom screen scores on hospital admission and 30-day readmissions.General hospital psychiatryArticle
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10 authors.
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Abstract
objectiveIdentifying the predictors of response to psychiatric and psychotherapeutic treatments may be useful for increasing treatment efficacy in pharmacoresistant depressive patients. The goal of this study was to examine the influence of dissociation, hope, personality trait, and selected demographic factors in treatment response of this group of patients.
methodsPharmacoresistant depressive inpatients were enrolled in the study. All patients completed Clinical Global Impression - both objective and subjective form (CGI), Beck Depression Inventory (BDI), and Beck Anxiety Inventory (BAI) at baseline and after 6 weeks of combined pharmacotherapy and psychotherapy (group cognitive-behavioral or group psychodynamic) treatment as an outcome measures. The Internalized Stigma of Mental Illness Scale (ISMI), Dissociative Experience Scale (DES), Adult Dispositional Hope Scale (ADHS), and Temperament and Character Inventory (TCI-R) were completed at the start of the treatment with the intention to find the predictors of treatment efficacy.
resultsThe study included 72 patients who were hospitalized for the pharmacoresistant major depression; 63 of them completed the study. The mean scores of BDI-II, BAI, subjCGI, and objCGI significantly decreased during the treatment. BDI-II relative change statistically significantly correlated with the total ISMI score, Discrimination Experience (ISMI subscale), and Harm Avoidance (TCI-R personality trait). According to stepwise regression, the strongest factors connected to BDI-II relative change were the duration of the disorder and Discrimination Experience (domain of ISMI). ObjCGI relative change significantly correlated with the level of dissociation (DES), the total ISMI score, hope in ADHS total score, and Self-Directedness (TCI-R). According to stepwise regression, the strongest factor connected to objCGI relative change was Discrimination Experience (domain of ISMI). The existence of comorbid personality disorder did not influence the treatment response.
conclusionAccording to the results of the present study, patients with pharmacoresistant depressive disorders, who have had more experience with discrimination because of their mental struggles, showed a poorer response to treatment.
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