Evidence map›Paper›PMID 27784971›Full record

Observational studyWorld journal of gastroenterology2016

Racial/ethnic disparities in hepatocellular carcinoma treatment and survival in California, 1988-2012.

Susan L Stewart, Sandy L Kwong, Christopher L Bowlus, Tung T Nguyen, Annette E Maxwell, Roshan Bastani, Eric W Chak, Moon S Chen

Open access · bronzeAbstract readObservational Study
In one paragraph

Observational study in World journal of gastroenterology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed, 3 pooled it
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 3 syntheses or guidelines pooled it, 60 citations in OpenAlex.

  1. Pooled it
  2. Racial and Ethnic Disparities in Hepatocellular Carcinoma Treatment Receipt in the United States: A Systematic Review and Meta-Analysis.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2024
    Pooled it
  3. Racial and Ethnic Disparities in Survival Among Patients With Hepatocellular Carcinoma in the United States: A Systematic Review and Meta-Analysis.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2022
    Pooled it
  4. Article
  5. County-Level Food Insecurity and Hepatocellular Carcinoma Risk: A Cross-Sectional Analysis.International journal of environmental research and public health · 2025
    Article
  6. Exploring disparities in healthcare utilization, cancer care experience, and beliefs about cancer among asian and hispanic cancer survivors.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
    Article
  7. Article
  8. Survival disparities among racial groups with hepatic malignant tumors.World journal of gastrointestinal oncology · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Susan L StewartSusan L Stewart, Division of Biostatistics, Department of Public Health Sciences, University of California, Davis School of Medicine, Sacramento, CA 95817, United States.
Sandy L KwongSusan L Stewart, Division of Biostatistics, Department of Public Health Sciences, University of California, Davis School of Medicine, Sacramento, CA 95817, United States.
Christopher L BowlusSusan L Stewart, Division of Biostatistics, Department of Public Health Sciences, University of California, Davis School of Medicine, Sacramento, CA 95817, United States.
Tung T NguyenSusan L Stewart, Division of Biostatistics, Department of Public Health Sciences, University of California, Davis School of Medicine, Sacramento, CA 95817, United States.
Annette E MaxwellSusan L Stewart, Division of Biostatistics, Department of Public Health Sciences, University of California, Davis School of Medicine, Sacramento, CA 95817, United States.
Roshan BastaniSusan L Stewart, Division of Biostatistics, Department of Public Health Sciences, University of California, Davis School of Medicine, Sacramento, CA 95817, United States.
Eric W ChakSusan L Stewart, Division of Biostatistics, Department of Public Health Sciences, University of California, Davis School of Medicine, Sacramento, CA 95817, United States.
Moon S ChenSusan L Stewart, Division of Biostatistics, Department of Public Health Sciences, University of California, Davis School of Medicine, Sacramento, CA 95817, United States.
University of California, Davis · US

Funding

Staff InvestigatorsP30CA093373 · NCI · UNIVERSITY OF CALIFORNIA DAVIS · PI Gina M Dayton · 2002 to 2026
$84.9M
NCI NIH HHS P30 CA093373
6 · The paper itself

Abstract

aimTo describe racial/ethnic differences in treatment and survival among liver cancer patients in a population-based cancer registry.

methodsInvasive cases of primary hepatocellular carcinoma,

resultsAfter adjustment for socio-demographic characteristics, time period, and stage of disease, compared to Whites, Laotian/Hmong [odds ratio (OR) = 0.30, 95%CI: 0.17-0.53], Cambodian (OR = 0.65, 95%CI: 0.45-0.96), AIAN (OR = 0.66, 95%CI: 0.46-0.93), Black (OR = 0.76, 95%CI: 0.67-0.86), and Hispanic (OR = 0.78, 95%CI: 0.72-0.84) patients were less likely, whereas Chinese (OR = 1.58, 95%CI: 1.42-1.77), Koreans (OR = 1.45, 95%CI: 1.24-1.70), Japanese (OR = 1.41, 95%CI: 1.15-1.72), and Vietnamese (OR = 1.26, 95%CI: 1.12-1.42) were more likely to receive surgical treatment. After adjustment for the same covariates and treatment, cause-specific mortality was higher for Laotian/Hmong [(hazard ratio (HR) = 1.50, 95%CI: 1.29-1.73)], Cambodians (HR = 1.35, 95%CI: 1.16-1.58), and Blacks (HR = 1.07, 95%CI: 1.01-1.13), and lower for Chinese (HR = 0.82, 95%CI: 0.77-0.86), Filipinos (HR = 0.84, 95%CI: 0.78-0.90), Vietnamese (HR = 0.85, 95%CI: 0.80-0.90), Koreans (HR = 0.90, 95%CI: 0.83-0.97), and Hispanics (HR = 0.91, 95%CI: 0.88-0.94); results were similar for all-cause mortality.

conclusionDisaggregated data revealed substantial racial/ethnic differences in liver cancer treatment and survival, demonstrating the need for development of targeted interventions to mitigate disparities.

Indexed as

Health Status DisparitiesAdultAgedAsianBlack or African AmericanCaliforniaCarcinoma, HepatocellularFemaleGeographyHealthcare DisparitiesHispanic or LatinoHumansKaplan-Meier EstimateLiver NeoplasmsMaleMiddle AgedDisparitiesHepatocellular carcinomaLiver cancerSurvivalTreatment

Identifiers

PMID27784971
PMCPMC5064040
OpenAlexW2531477027

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.