Evidence map›Paper›PMID 27784595›Full record

ReviewThe Journal of investigative dermatology2017

Emerging Skin T-Cell Functions in Response to Environmental Insults.

Jutamas Suwanpradid, Zachary E Holcomb, Amanda S MacLeod

Abstract readReview
In one paragraph

Review in The Journal of investigative dermatology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Therapeutic Cancer Vaccines for Nonmelanoma Skin Cancer.Current treatment options in oncology · 2023
    Review
  6. Review
  7. [Research advances on the mechanism of dendritic epidermal T lymphocytes in wound healing].Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns · 2021
    Article
  8. Review
  9. Review
  10. Review
  11. Article
  12. Article
  13. Skin - a vast organ with immunological function (Review).Experimental and therapeutic medicine · 2020
    Review
  14. Review
  15. Article
  16. The Role of the Immune System in Cutaneous Squamous Cell Carcinoma.International journal of molecular sciences · 2019
    Review
  17. The Dynamics of the Skin's Immune System.International journal of molecular sciences · 2019
    Review
  18. Review
  19. Regulatory T cells in skin.Immunology · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jutamas SuwanpradidDepartment of Dermatology, Duke University Medical Center, Durham, North Carolina, USA.
Zachary E HolcombDepartment of Dermatology, Duke University Medical Center, Durham, North Carolina, USA; Duke University School of Medicine, Durham, North Carolina, USA.
Amanda S MacLeodDepartment of Dermatology, Duke University Medical Center, Durham, North Carolina, USA; Department of Immunology, Duke University Medical Center, Durham, North Carolina, USA; Pinnell Center for Investigative Dermatology and Skin Disease Research Center, Duke University Medical Center, Durham, North Carolina, USA. Electronic address: Amanda.MacLeod@duke.edu.

Funding

Women's Cancer Research ProgramP30CA014236 · NCI · DUKE UNIVERSITY · PI DONNA NIEDZWIECKI · 1985 to 2026
$174.8M
Tissue Procurement and Analysis CoreP30AR066527 · NIAMS · DUKE UNIVERSITY · PI LEVINSON, HOWARD · 2014 to 2015
$1.3M
ATP in Skin ImmunityK08AR063729 · NIAMS · SCRIPPS RESEARCH INSTITUTE, THE · PI MACLEOD, AMANDA S · 2013 to 2017
$636k
NCI NIH HHS P30 CA014236NIAMS NIH HHS K08 AR063729NIAMS NIH HHS P30 AR066527
6 · The paper itself

Abstract

Skin is the primary barrier between the body and the outside world, functioning not only as a physical barrier, but also as an immunologic first line of defense. A large number of T cells populate the skin. This review highlights the ability of these cutaneous T cells to regulate skin-specific environmental threats, including microbes, injuries, solar UV radiation, and allergens. Since much of this knowledge has been advanced from murine studies, we focus our review on how the mouse state has informed the human state, emphasizing the key parallels and differences.

Indexed as

AnimalsDermatitis, Allergic ContactDrug EruptionsHumansMiceMicrobiotaSkinT-LymphocytesUltraviolet RaysWound Healing

Identifiers

PMID27784595
PMCPMC5552043

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.