Evidence map›Paper›PMID 27784305›Full record

ReviewMolecular cancer2016

Emerging roles of T helper 17 and regulatory T cells in lung cancer progression and metastasis.

Erin A Marshall, Kevin W Ng, Sonia H Y Kung, Emma M Conway, Victor D Martinez, Elizabeth C Halvorsen, David A Rowbotham, Emily A Vucic, Adam W Plumb, Daiana D Becker-Santos and 8 more

Open access · goldAbstract readReview
In one paragraph

Review in Molecular cancer, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 137 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
137citing papers in PubMed, 1 pooled it
5.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

137 citing papers in PubMed, 1 synthesis or guideline pooled it, 258 citations in OpenAlex.

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77 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 2 institutions in 1 country.

Erin A MarshallDepartment of Integrative Oncology, British Columbia Cancer Agency, Vancouver, Canada.
Kevin W NgDepartment of Integrative Oncology, British Columbia Cancer Agency, Vancouver, Canada.
Sonia H Y KungDepartment of Integrative Oncology, British Columbia Cancer Agency, Vancouver, Canada. skung@bccrc.ca.
Emma M ConwayDepartment of Integrative Oncology, British Columbia Cancer Agency, Vancouver, Canada.
Victor D MartinezDepartment of Integrative Oncology, British Columbia Cancer Agency, Vancouver, Canada.
Elizabeth C HalvorsenDepartment of Integrative Oncology, British Columbia Cancer Agency, Vancouver, Canada.
David A RowbothamDepartment of Integrative Oncology, British Columbia Cancer Agency, Vancouver, Canada.
Emily A VucicDepartment of Integrative Oncology, British Columbia Cancer Agency, Vancouver, Canada.
Adam W PlumbDepartments of Microbiology and Immunology, University of British Columbia, Vancouver, Canada.
Daiana D Becker-SantosDepartment of Integrative Oncology, British Columbia Cancer Agency, Vancouver, Canada.
Katey S S EnfieldDepartment of Integrative Oncology, British Columbia Cancer Agency, Vancouver, Canada.
Jennifer Y KennettDepartment of Integrative Oncology, British Columbia Cancer Agency, Vancouver, Canada.
Kevin L BennewithDepartment of Integrative Oncology, British Columbia Cancer Agency, Vancouver, Canada.
William W LockwoodDepartment of Integrative Oncology, British Columbia Cancer Agency, Vancouver, Canada.
Stephen LamDepartment of Integrative Oncology, British Columbia Cancer Agency, Vancouver, Canada.
John C EnglishDepartment of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, Canada.
Ninan AbrahamDepartments of Microbiology and Immunology, University of British Columbia, Vancouver, Canada.
Wan L LamDepartment of Integrative Oncology, British Columbia Cancer Agency, Vancouver, Canada. wanlam@bccrc.ca.
BC Cancer Agency · CAUniversity of British Columbia · CA

Funding

CIHR FDN-143345CIHR MOP-110949CIHR MOP-123273
6 · The paper itself

Abstract

Lung cancer is a leading cause of cancer-related deaths worldwide. Lung cancer risk factors, including smoking and exposure to environmental carcinogens, have been linked to chronic inflammation. An integral feature of inflammation is the activation, expansion and infiltration of diverse immune cell types, including CD4

Indexed as

AnimalsDisease ProgressionHumansLung NeoplasmsMiceNeoplasm MetastasisTh17 CellsT-Lymphocytes, RegulatoryTumor MicroenvironmentCancer immunologyIL-17InflammationLung cancerPrognosisRegulatory T cellTh17TregTumorigenesisTumor microenvironment

Identifiers

PMID27784305
PMCPMC5082389
OpenAlexW2541139800

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.