Evidence map›Paper›PMID 27783988›Full record

ArticleOncotarget2016

Kinetic changes of intestinal microbiota in the course of intestinal sensitization.

Liang Xiao, Bo Yang, Xiaoyu Liu, Yan Luo, Qiongmei Ji, Zhong Wen, Zhigang Liu, Ping-Chang Yang

Open access · diamondAbstract read
In one paragraph

Article in Oncotarget, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Liang XiaoThe Research Center of Allergy and Immunology, Shenzhen University School of Medicine, Shenzhen 518060, China.
Bo YangThe Research Center of Allergy and Immunology, Shenzhen University School of Medicine, Shenzhen 518060, China.
Xiaoyu LiuThe Research Center of Allergy and Immunology, Shenzhen University School of Medicine, Shenzhen 518060, China.
Yan LuoThe Research Center of Allergy and Immunology, Shenzhen University School of Medicine, Shenzhen 518060, China.
Qiongmei JiThe Research Center of Allergy and Immunology, Shenzhen University School of Medicine, Shenzhen 518060, China.
Zhong WenDepartment of Otolaryngology, Zhujiang Hospital, Southern Medical University, Guangzhou 510280, China.
Zhigang LiuThe Research Center of Allergy and Immunology, Shenzhen University School of Medicine, Shenzhen 518060, China.
Ping-Chang YangThe Research Center of Allergy and Immunology, Shenzhen University School of Medicine, Shenzhen 518060, China.
Shenzhen University · CNBGI Group (China) · CNZhujiang Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Food allergy (FA) is an adverse immune response to certain innocent food. It is estimated about 2% to 6% of the general population suffer from FA. Symptoms of a food allergic reaction may involve the gastrointestinal tract or/and other organs. The gut microbiota plays a critical role in diet-induced health problems. Whether the changes in the composition of the intestinal microbiota regulate allergic responses to food remains poorly understood. Thus, we created an FA animal model, sequenced the V4-V5 regions of 16S rRNA genes to characterize the genera abundance of gut microbiota. The results showed that mice under FA condition showed different gut bacterial structures. Diverse distribution of the bacterial species was identified between FA and control groups. FA altered the components of intestinal Microbiota in mice. The dysbiosis of the gut metagenome correlated with the development of the FA.

Indexed as

Gastrointestinal MicrobiomeAnimalsBacteriaCD4-Positive T-LymphocytesCells, CulturedDendritic CellsDisease Models, AnimalDNA, BacterialDysbiosisFood HypersensitivityIntestinal MucosaJejunumKineticsMetagenomeMice, Inbred BALB CPhenotypeDNA, Bacterial16S rRNAanimal modelfood allergyintestinemicrobiota

Identifiers

PMID27783988
PMCPMC5348386
OpenAlexW2537912640

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.