Evidence map›Paper›PMID 27783861›Full record

ReviewComprehensive Physiology2016

Undiscovered Physiology of Transcript and Protein Networks.

Emma Monte, Manuel Rosa-Garrido, Thomas M Vondriska, Jessica Wang

Abstract readReview
In one paragraph

Review in Comprehensive Physiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Emma MonteDepartment of Anesthesiology & Perioperative Medicine, David Geffen School of Medicine, University of California, Los Angeles, USA.
Manuel Rosa-GarridoDepartment of Anesthesiology & Perioperative Medicine, David Geffen School of Medicine, University of California, Los Angeles, USA.
Thomas M VondriskaDepartment of Anesthesiology & Perioperative Medicine, David Geffen School of Medicine, University of California, Los Angeles, USA.
Jessica WangDepartment of Medicine/Cardiology, David Geffen School of Medicine, University of California, Los Angeles, USA.

Funding

Functional Validation of Myh14 in Stress-Induced Cardiac Remodeling.K08HL133491 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI WANG, JESSICA J · 2017 to 2021
$875k
NHLBI NIH HHS K08 HL133491
6 · The paper itself

Abstract

The past two decades have witnessed a rapid evolution in our ability to measure RNA and protein from biological systems. As a result, new principles have arisen regarding how information is processed in cells, how decisions are made, and the role of networks in biology. This essay examines this technological evolution, reviewing (and critiquing) the conceptual framework that has emerged to explain how RNA and protein networks control cellular function. We identify how future investigations into transcriptomes, proteomes, and other cellular networks will enable development of more robust, quantitative models of cellular behavior whilst also providing new avenues to use knowledge of biological networks to improve human health. © 2016 American Physiological Society. Compr Physiol 6:1851-1872, 2016.

Indexed as

AnimalsHumansProteinsProteomeRNASequence Analysis, RNATranscriptomeProteinsProteomeRNA

Identifiers

PMID27783861
PMCPMC10751805

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.