Evidence map›Paper›PMID 27783846›Full record

ArticleJournal of clinical periodontology2017

Periodontitis is not associated with metabolic risk during the fourth decade of life.

Dara M Shearer, W Murray Thomson, Jonathan M Broadbent, Jim Mann, Richie Poulton

Open access · greenAbstract read
In one paragraph

Article in Journal of clinical periodontology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Dara M ShearerDepartment of Oral Sciences, Faculty of Dentistry, University of Otago, Dunedin, New Zealand.
W Murray ThomsonDepartment of Oral Sciences, Faculty of Dentistry, University of Otago, Dunedin, New Zealand.
Jonathan M BroadbentDepartment of Oral Rehabilitation, Faculty of Dentistry, University of Otago, Dunedin, New Zealand.
Jim MannDepartment of Human Nutrition, University of Otago, Dunedin, New Zealand.
Richie PoultonDunedin Multidisciplinary Health and Development Research Unit, University of Otago, Dunedin, New Zealand.
University of Otago · NZDunedin Public Hospital · NZFaculty (United Kingdom) · GB

Funding

Is mental disorder a preventable cause of age-related disease? The Dunedin Study.R01AG032282 · NIA · DUKE UNIVERSITY · PI CASPI, AVSHALOM, MOFFITT, TERRIE E · 2009 to 2025
$9.5M
SELF-REPORT DELINQUENCY: A LONGITUDINAL STUDYR01MH045070 · NIMH · UNIVERSITY OF WISCONSIN MADISON · PI MOFFITT, TERRIE EDITH · 1989 to 2006
$2.5M
Personality and Health from Childhood to AdulthoodR01MH049414 · NIMH · UNIVERSITY OF WISCONSIN-MADISON · PI CASPI, AVSHALOM · 1997 to 2006
$1.8M
Oral health disparities in the first 4 decades of lifeR01DE015260 · NIDCR · UNIVERSITY OF OTAGO · PI THOMSON, WILLIAM MURRAY · 2004 to 2007
$591k
Generating new knowledge to support reversibility interventionsR01AG048895 · NIA · DUKE UNIVERSITY · PI MOFFITT, TERRIE E · 2014 to 2015
$311k
Medical Research Council G0100527Medical Research Council G0601483Medical Research Council MR/K00381XMedical Research Council MR/P005918/1NIA NIH HHS R01 AG032282NIA NIH HHS R01 AG048895NIDCR NIH HHS R01 DE015260NIMH NIH HHS R01 MH045070NIMH NIH HHS R01 MH049414
6 · The paper itself

Abstract

aimTo examine associations between periodontitis and developmental trajectories of glycated haemoglobin (HbA1c) during the third and fourth decades in an initially healthy sample. MATERIALS AND

methodsHbA1c data collected at ages 26, 32 and 38 in the prospective Dunedin Multidisciplinary Health and Development Study were used to assign study members (n = 893) to trajectories applying group-based trajectory modelling (GBTM). The model allowed the statistical linking of baseline demographic, smoking and waist-height ratio covariates to group membership probability; and added a time-varying covariate (periodontitis) to the trajectories themselves to examine whether events that occurred during the course of the trajectory altered its course.

resultsThree HbA1c trajectory groups were identified: "Low" (n = 98, 11.0%); "Medium" (n = 482, 54.0%); and "High" (n = 313, 35.0%) with mean HbA1c of 29.6, 34.1 and 38.7 mmol/mol, respectively, at age 38. Having periodontitis at 32 and 38 was associated with an upward shift in the trajectories. However, none of the associations were statistically significant.

conclusionsPeriodontitis was not found to be associated with dysglycaemia over 12 years from early adulthood into early middle age. This suggests that any influence periodontitis may have on dysglycaemia develops later in life.

Indexed as

AdultAge FactorsFemaleGlucose Metabolism DisordersGlycated HemoglobinHumansMalePeriodontitisProspective StudiesGlycated Hemoglobinglycated haemoglobinlongitudinalperiodontitissmokingtype 2 diabeteswaist-height ratio

Identifiers

PMID27783846
PMCPMC6547373
OpenAlexW2545430012

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.