Evidence map›Paper›PMID 27783539›Full record

ArticleAmerican journal of respiratory and critical care medicine2017

A New Approach for Identifying Patients with Undiagnosed Chronic Obstructive Pulmonary Disease.

Fernando J Martinez, David Mannino, Nancy Kline Leidy, Karen G Malley, Elizabeth D Bacci, R Graham Barr, Russ P Bowler, MeiLan K Han, Julia F Houfek, Barry Make and 6 more

Erratum issued Registry-linked trialAbstract readMulticenter Study
In one paragraph

Article in American journal of respiratory and critical care medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT01880177 (A Study Designed to Develop and Validate a New Screening Measure for Identifying Undiagnosed At-Risk COPD Cases), which is not on this map. Cited by 81 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
81citing papers in PubMed, 3 pooled it
6.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01880177 completednot on this map

A Study Designed to Develop and Validate a New Screening Measure for Identifying Undiagnosed At-Risk COPD Cases

TypeobservationalSponsorUniversity of MichiganRan2013 to 2015Enrolled346ConditionsChronic Obstructive Pulmonary Disease (COPD)
3 · Its place in the literature

Who cites it

81 citing papers in PubMed, 3 syntheses or guidelines pooled it, 150 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Performance of alternative COPD case-finding tools: a systematic review and meta-analysis.European respiratory review : an official journal of the European Respiratory Society · 2021
    Pooled it
  4. Trial
  5. Trial
  6. Trial
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Prospective COPD Case Finding in a Lung Cancer Screening Program: A Pilot Study.Chronic obstructive pulmonary diseases (Miami, Fla.) · 2025
    Article
  16. Article
  17. Early enteral nutrition in critically-ill patients.World journal of critical care medicine · 2025
    Review
  18. Article
  19. Towards early detection and disease interception of COPD across the lifespan.European respiratory review : an official journal of the European Respiratory Society · 2025
    Review
  20. A Two-Staged, Risk-Stratified Strategy Combining FEVRespirology (Carlton, Vic.) · 2025
    Observational

21 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

16 authors at 11 institutions in 3 countries.

Fernando J Martinez1 Joan and Sanford I. Weill Department of Medicine, Weill Cornell Medical College, New York, New York.
David Mannino2 Department of Preventive Medicine and Environmental Health, University of Kentucky, Lexington, Kentucky.
Nancy Kline Leidy3 Outcomes Research, Evidera, Bethesda, Maryland.
Karen G Malley3 Outcomes Research, Evidera, Bethesda, Maryland.
Elizabeth D Bacci4 Outcomes Research, Evidera, Seattle, Washington.
R Graham Barr5 Department of Medicine and.
Russ P Bowler7 Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, National Jewish Health, Denver, Colorado.
MeiLan K Han8 Division of Pulmonary and Critical Care, University of Michigan, Ann Arbor, Michigan.
Julia F Houfek9 College of Nursing and.
Barry Make7 Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, National Jewish Health, Denver, Colorado.
Catherine A Meldrum8 Division of Pulmonary and Critical Care, University of Michigan, Ann Arbor, Michigan.
Stephen Rennard10 Pulmonary, Critical Care, Allergy and Sleep Medicine Division, Department of Internal Medicine, University of Nebraska Medical Center, Omaha, Nebraska.
Byron Thomashow12 Division of Pulmonary, Allergy and Critical Care Medicine, Columbia University, New York, New York.
John Walsh13 COPD Foundation, Washington, District of Columbia; and.
Barbara P Yawn14 Department of Family and Community Health, University of Minnesota, Minneapolis, Minnesota.
High-Risk-COPD Screening Study Group *
National Jewish Health · USOutcomes Research Consortium · USUniversity of Michigan · USAstraZeneca (United Kingdom) · GBColumbia University · USColumbia University Irving Medical Center · USCOPD Foundation · USCornell University · USOkinawa Prefectural College of Nursing · JPUniversity of Kentucky · USUniversity of Minnesota · US

Funding

Genetic Epidemiology of COPDU01HL089897 · NHLBI · NATIONAL JEWISH HEALTH · PI CRAPO, JAMES D · 2007 to 2021
$56.9M
Metabolomic signatures of empysema and COPD progression in the COPDGene cohortR01HL089897 · NHLBI · NATIONAL JEWISH HEALTH · PI CRAPO, JAMES D · 2012 to 2016
$31.1M
Genetic Epidemiology of COPDU01HL089856 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI SILVERMAN, EDWIN K · 2007 to 2021
$20.7M
(2 of 2) Genetic Epidemiology of COPDR01HL089856 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI SILVERMAN, EDWIN K · 2012 to 2016
$18.9M
Design and Testing of tools to Identify individuals at high risk for COPD^ 73R01HL114055 · NHLBI · WEILL MEDICAL COLL OF CORNELL UNIV · PI LEIDY, NANCY KLINE, MANNINO, DAVID · 2012 to 2014
$2.4M
NHLBI NIH HHS R01 HL089856NHLBI NIH HHS R01 HL089897NHLBI NIH HHS R01 HL114055NHLBI NIH HHS U01 HL089856NHLBI NIH HHS U01 HL089897
6 · The paper itself

Abstract

rationaleChronic obstructive pulmonary disease (COPD) is often unrecognized and untreated.

objectivesTo develop a method for identifying undiagnosed COPD requiring treatment with currently available therapies (FEV

methodsWe conducted a multisite, cross-sectional, case-control study in U.S. pulmonary and primary care clinics that recruited subjects from primary care settings. Cases were patients with COPD and at least one exacerbation in the past year or FEV MEASUREMENTS AND MAIN

resultsPEF and spirometry were recorded in 186 cases and 160 control subjects. The mean (SD) age of the sample population was 62.7 (10.1) years; 55% were female; 86% were white; and 16% had never smoked. The mean FEV

conclusionsCAPTURE with PEF can identify patients with COPD who would benefit from currently available therapy and require further diagnostic evaluation. Clinical trial registered with clinicaltrials.gov (NCT01880177).

Indexed as

Surveys and QuestionnairesAdultAgedAged, 80 and overCase-Control StudiesCross-Sectional StudiesFemaleForced Expiratory VolumeHumansLungMaleMiddle AgedPeak Expiratory Flow RateProspective StudiesPulmonary Disease, Chronic ObstructiveRisk Factorschronic obstructive pulmonary diseaseprimary carequestionnairerandom forestsscreening

Identifiers

PMID27783539
PMCPMC5363964
OpenAlexW2545337398

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.