ArticleAccounts of chemical research2016
The Remarkable Character of Porphobilinogen Synthase.
Article in Accounts of chemical research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed.
- Milestones in the Elucidation of Heme Biosynthesis.Chemical reviews · 2026Review
- Root Structural and Metabolic Plasticity Confers Tolerance to Salinity in Wild Barley Species Grown Under Waterlogging.Plant, cell & environment · 2026Article
- Metabolic engineering ofApplied and environmental microbiology · 2026Article
- Nutrigenomic profiling identifies ZIP10 (Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Mediation of Pre-Pregnancy Body Mass Index and Dietary Patterns with Relation to Vitamin D and Erythropoiesis-Related Micronutrients in Pregnant Women.International journal of medical sciences · 2026Article
- Exploring genetic diversity and genomic insights of Bacillus subtilis isolates from cassava rhizosphere using molecular barcoding and whole genome sequencing.Scientific reports · 2025Article
- Zinc transporter ZIP10 supports zinc homeostasis and myoglobin biosynthesis in differentiating C2C12 myoblasts.Frontiers in cell and developmental biology · 2025Article
- Chlorophyll and Carotenoid Metabolism Varies with Growth Temperatures among Tea Genotypes with Different Leaf Colors inInternational journal of molecular sciences · 2024Article
- Allostreptopyrroles A-E, β-alkylpyrrole derivatives from an actinomyceteBeilstein journal of organic chemistry · 2024Article
- Biochemical and molecular characterization of a novel porphobilinogen synthase from Corynebacterium glutamicum.World journal of microbiology & biotechnology · 2023Article
- Cellular Zinc Deficiency Impairs Heme Biosynthesis in Developing Erythroid Progenitors.Nutrients · 2023Article
- More indications for redox-sensitive cysteine residues of the Arabidopsis 5-aminolevulinate dehydratase.Frontiers in plant science · 2023Article
- In Silico Exploration ofBiomolecules · 2022Article
- Naturally occurring cancer-associated mutations disrupt oligomerization and activity of protein arginine methyltransferase 1 (PRMT1).The Journal of biological chemistry · 2021Article
- Article
- In silico Studies on the Interaction between Mpro and PLpro From SARS-CoV-2 and Ebselen, its Metabolites and Derivatives.Molecular informatics · 2021Article
- Manipulation of a cation-π sandwich reveals conformational flexibility in phenylalanine hydroxylase.Biochimie · 2021Article
- Heme biosynthesis depends on previously unrecognized acquisition of iron-sulfur cofactors in human amino-levulinic acid dehydratase.Nature communications · 2020Article
- The SeComputational toxicology (Amsterdam, Netherlands) · 2020Article
- Wrangling Shape-Shifting Morpheeins to Tackle Disease and Approach Drug Discovery.Frontiers in molecular biosciences · 2020Review
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Abstract
Porphobilinogen synthase (PBGS), also known as 5-aminolevulinate dehydratase, is an essential enzyme in the biosynthesis of all tetrapyrroles, which function in respiration, photosynthesis, and methanogenesis. Throughout evolution, PBGS adapted to a diversity of cellular niches and evolved to use an unusual variety of metal ions both for catalytic function and to control protein multimerization. With regard to the active site, some PBGSs require Zn
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