Evidence map›Paper›PMID 27783161›Full record

ArticleInternational journal of colorectal disease2017

Consequences of CT colonography in stenosing colorectal cancer.

J F Huisman, L W Leicher, E de Boer, H L van Westreenen, J W de Groot, F A Holman, P C van de Meeberg, Pejm Sallevelt, Kcmj Peeters, Mnjm Wasser and 2 more

Abstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in International journal of colorectal disease, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Guideline
  2. PreoperativeFrontiers in surgery · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. CT colonography in patients with stenosing colorectal cancer.International journal of colorectal disease · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

J F HuismanDepartment of Gastroenterology and Hepatology, P.O. box 10400, Isala, 8000 GK, Zwolle, the Netherlands. j.f.huisman@isala.nl.
L W LeicherDepartment of Gastroenterology and Hepatology, P.O. box 10400, Isala, 8000 GK, Zwolle, the Netherlands.
E de BoerDepartment of Radiology, Isala, Zwolle, the Netherlands.
H L van WestreenenDepartment of Surgery, Isala, Zwolle, the Netherlands.
J W de GrootDepartment of Medical Oncology, Isala, Zwolle, the Netherlands.
F A HolmanDepartment of Surgery, Leiden University Medical Center, Leiden, the Netherlands.
P C van de MeebergDepartment of Gastroenterology and Hepatology, Slingeland hospital, Doetinchem, the Netherlands.
Pejm SalleveltDepartment of Radiology, Slingeland hospital, Doetinchem, the Netherlands.
Kcmj PeetersDepartment of Surgery, Leiden University Medical Center, Leiden, the Netherlands.
Mnjm WasserDepartment of Radiology, Leiden University Medical Center, Leiden, the Netherlands.
Hfa VasenDept of Gastroenterology and Hepatology, Leiden University Medical Center, Leiden, the Netherlands.
W H de Vos Tot Nederveen CappelDepartment of Gastroenterology and Hepatology, P.O. box 10400, Isala, 8000 GK, Zwolle, the Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn patients with stenosing colorectal cancer (CRC), visualization of the entire colon prior to surgery is recommended to exclude synchronous tumors. Therefore, most centers combine computed tomographic colonography (CTC) with staging CT. The aims of this study were to evaluate the yield and clinical implications of CTC.

methodsIn this multicenter retrospective study, patients with stenosing CRC that underwent CTC and subsequent surgery between April 2013 and November 2015 were included. Result of the CTC, its influence on the surgical treatment plan, and final histology report were evaluated.

resultsOne hundred sixty-two patients with stenosing CRC were included. Nine (5.6 %) synchronous cancers proximal to the stenosing tumor were suspected with CTC. In four of nine patients, the CTC did not change the primary surgical plan because the tumors were located in the same surgical segment. In five of nine patients, CTC changed the surgical treatment plan. Three of these five patients underwent an extended resection and the presence of the tumors was confirmed. Two of these three synchronous CRCs were also visible on abdominal staging CT. In the other two patients, the result of CTC was false positive which led to an unnecessary extended resection in one patient.

conclusionThe yield of CTC was relatively low. In only three patients (1.9 %), CTC correctly changed the primary surgical plan, but in two of them, the tumor was also visible on abdominal staging CT. Moreover, in two patients, CTC was false positive. The clinical value of CTC in stenosing CRC appears to be limited.

Indexed as

ColonoscopyTomography, X-Ray ComputedAgedColorectal NeoplasmsConstriction, PathologicFemaleHumansMalePostoperative CareColorectal cancerCT colonographyObstructiveStenosing

Identifiers

PMID27783161

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.