Evidence map›Paper›PMID 27782882›Full record

ArticleeLife2016

Release-dependent feedback inhibition by a presynaptically localized ligand-gated anion channel.

Seika Takayanagi-Kiya, Keming Zhou, Yishi Jin

Open access · goldAbstract read
In one paragraph

Article in eLife, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 36 citations in OpenAlex.

  1. Article
  2. Molecular organization of central cholinergic synapses.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  3. Life science alliance · 2024
    Article
  4. Article
  5. Article
  6. A Novel and Functionally Diverse Class of Acetylcholine-Gated Ion Channels.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023
    Article
  7. Neuronally produced betaine acts via a ligand-gated ion channel to control behavioral states.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. The auxiliary glutamate receptor subunit dSol-1 promotes presynaptic neurotransmitter release and homeostatic potentiation.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Journal of neurogenetics
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Seika Takayanagi-KiyaSection of Neurobiology, Division of Biological Sciences, University of California, San Diego, San Diego, United States.
Keming ZhouSection of Neurobiology, Division of Biological Sciences, University of California, San Diego, San Diego, United States.
Yishi JinSection of Neurobiology, Division of Biological Sciences, University of California, San Diego, San Diego, United States.ORCID 0000-0002-9371-9860
Howard Hughes Medical Institute · USUniversity of California San Diego · US

Funding

GABAERGIC NEURON DIFFERENTIATION IN C ELEGANSR01NS035546 · NINDS · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI JIN, YISHI · 1996 to 2016
$5.3M
Howard Hughes Medical InstituteNINDS NIH HHS R01 NS035546
6 · The paper itself

Abstract

Presynaptic ligand-gated ion channels (LGICs) have long been proposed to affect neurotransmitter release and to tune the neural circuit activity. However, the understanding of their in vivo physiological action remains limited, partly due to the complexity in channel types and scarcity of genetic models. Here we report that

Indexed as

Feedback, PhysiologicalAnimalsCaenorhabditis elegansCaenorhabditis elegans ProteinsChloride ChannelsCholinergic NeuronsEvoked PotentialsMotor NeuronsNeurotransmitter AgentsPresynaptic TerminalsCaenorhabditis elegans ProteinsChloride ChannelsLGC-46 protein, C elegansNeurotransmitter AgentsACC channelsC. elegansneurosciencepresynaptic autoreceptorSV release kinetics

Identifiers

PMID27782882
PMCPMC5102579
OpenAlexW2540907583

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.