Evidence map›Paper›PMID 27782881›Full record

ArticleeLife2016

Proteolytic maturation of α

Ivan Kadurin, Laurent Ferron, Simon W Rothwell, James O Meyer, Leon R Douglas, Claudia S Bauer, Beatrice Lana, Wojciech Margas, Orpheas Alexopoulos, Manuela Nieto-Rostro and 2 more

Open access · goldAbstract read
In one paragraph

Article in eLife, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 1 pooled it
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 1 synthesis or guideline pooled it, 49 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Review
  5. Review
  6. Autism-Linked Mutations in αPharmaceuticals (Basel, Switzerland) · 2024
    Article
  7. Article
  8. Article
  9. Review
  10. Pathophysiological Roles of Auxiliary Calcium Channel αHandbook of experimental pharmacology · 2023
    Article
  11. Article
  12. Involvement of CaThe Journal of physiology · 2022
    Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. The life cycle of voltage-gated CaNeuronal signaling · 2021
    Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 2 countries.

Ivan KadurinDepartment of Neuroscience, Physiology and Pharmacology, University College London, London, United Kingdom.
Laurent FerronDepartment of Neuroscience, Physiology and Pharmacology, University College London, London, United Kingdom.
Simon W RothwellDepartment of Neuroscience, Physiology and Pharmacology, University College London, London, United Kingdom.
James O MeyerDepartment of Neuroscience, Physiology and Pharmacology, University College London, London, United Kingdom.
Leon R DouglasDepartment of Neuroscience, Physiology and Pharmacology, University College London, London, United Kingdom.
Claudia S BauerDepartment of Neuroscience, Physiology and Pharmacology, University College London, London, United Kingdom.
Beatrice LanaDepartment of Neuroscience, Physiology and Pharmacology, University College London, London, United Kingdom.
Wojciech MargasDepartment of Neuroscience, Physiology and Pharmacology, University College London, London, United Kingdom.
Orpheas AlexopoulosDepartment of Neuroscience, Physiology and Pharmacology, University College London, London, United Kingdom.
Manuela Nieto-RostroDepartment of Neuroscience, Physiology and Pharmacology, University College London, London, United Kingdom.
Wendy S PrattDepartment of Neuroscience, Physiology and Pharmacology, University College London, London, United Kingdom.
Annette C DolphinDepartment of Neuroscience, Physiology and Pharmacology, University College London, London, United Kingdom.ORCID 0000-0003-4626-4856
California Institute of Technology · USCancer Research UK · GBUniversity College London · GB

Funding

Medical Research Council G0801756Medical Research Council G0901758Medical Research Council MR/J013285/1Wellcome TrustWellcome Trust 098360/Z/12/Z
6 · The paper itself

Abstract

The auxiliary α

Indexed as

Protein Processing, Post-TranslationalAnimalsCalcium Channels, N-TypeMiceModels, BiologicalNeuronsProtein TransportProteolysisRabbitsRatsCacna1b protein, ratCalcium Channels, N-TypebiochemistryCa2+ channelselectrophysiologymouseneuronneurosciencerat

Identifiers

PMID27782881
PMCPMC5092059
OpenAlexW2545800264

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.