Evidence map›Paper›PMID 27782692›Full record

ArticleMedical physics2016

Interventional dual-energy imaging-Feasibility of rapid kV-switching on a C-arm CT system.

K Müller, S Datta, M Ahmad, J-H Choi, T Moore, L Pung, C Niebler, G E Gold, A Maier, R Fahrig

Abstract read
In one paragraph

Article in Medical physics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Flat-panel dual-energy head computed tomography in the angiography suite after thrombectomy for acute stroke: A clinical feasibility study.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2026
    Article
  2. One-Step Material Decomposition Using Spectral Diffusion Posterior Sampling in Sparse-View Dual-Layer CT.Proceedings of SPIE--the International Society for Optical Engineering · 2026
    Article
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  8. Approaches for Three Material Decomposition using a Triple-Layer Flat-Panel Detector.Proceedings of SPIE--the International Society for Optical Engineering · 2023
    Article
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  14. Prototype system for interventional dual-energy subtraction angiography.Proceedings of SPIE--the International Society for Optical Engineering · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

K MüllerRadiological Sciences Lab, Stanford University, Stanford, California 94305.
S DattaSiemens Medical Solutions, Inc., Malvern, Pennsylvania 19355.
M AhmadRadiological Sciences Lab, Stanford University, Stanford, California 94305.
J-H ChoiRadiological Sciences Lab, Stanford University, Stanford, California 94305.
T MooreSiemens Medical Solutions, Inc., Malvern, Pennsylvania 19355.
L PungSiemens Medical Solutions, Inc., Malvern, Pennsylvania 19355.
C NieblerDepartment of Electrical Engineering, Technische Hochschule Nürnberg, Nürnberg 90489, Germany.
G E GoldDepartment of Radiology, Stanford University Stanford, California 94305; Department of Orthopaedic Surgery, Stanford University, Stanford, California 94305; and Department of Bioengineering, Stanford University, Stanford, California 94305.
A MaierPattern Recognition Lab, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen 91058, Germany.
R FahrigRadiological Sciences Lab, Stanford University, Stanford, California 94305.

Funding

Axiom zeego shared instrument grantS10RR026714 · NCRR · STANFORD UNIVERSITY · PI FAHRIG, REBECCA · 2010 to 2010
$500k
NCRR NIH HHS S10 RR026714
6 · The paper itself

Abstract

purposeIn the last years, dual-energy CT imaging has shown clinical value, thanks to its ability to differentiate materials based on their atomic number and to exploit different properties of images acquired at two different energies. C-arm CT systems are used to guide procedures in the interventional suite. Until now, there are no commercially available systems that employ dual-energy material decomposition. This paper explores the feasibility of implementing a fast kV-switching technique on a clinically available angiographic system for acquiring dual-energy C-arm CT images.

methodsAs an initial proof of concept, a fast kV-switching approach was implemented on an angiographic C-arm system and the peak tube voltage during 3D rotational scans was measured. The tube voltage measurements during fast kV-switching scans were compared to corresponding measurements on kV-constant scans. Additionally, to prove stability of the requested exposure parameters, the accuracy of the delivered tube current and pulse width were also recorded and compared. In a first phantom experiment, the voxel intensity values of the individual tube voltage components of the fast kV-switching scans were compared to their corresponding kV-constant scans. The same phantom was used for a simple material decomposition between different iodine concentrations and pure water using a fast kV-switching protocol of 81 and 125 kV. In the last experiment, the same kV-switching protocol as in the phantom scan was used in an in vivo pig study to demonstrate the clinical feasibility.

resultsDuring rapid kV-switching acquisitions, the measured tube voltage of the x-ray tube during fast switching scans has an absolute deviation of 0.23 ± 0.13 kV compared to the measured tube voltage produced during kV-constant acquisitions. The stability of the peak tube voltage over different scan requests was about 0.10 kV for the low and 0.46 for the high energy kV-switching scans and less than 0.1 kV for kV-constant scans, indicating slightly lower stability for kV-switching scans. The tube current resulted in a relative deviation of -1.6% for the low and 6.6% overestimation for the high tube voltage of the kV-switching scans compared to the kV-constant scans. The pulse width showed no deviation for the longer pulse width and only minor deviations (0.02 ± 0.02 ms) for the shorter pulse widths compared to the kV-constant scans. The phantom experiment using different iodine concentrations showed an accurate correlation (R

conclusionsThe feasibility of dual-energy imaging using a fast kV-switching method on an angiographic C-arm CT system was investigated. Direct measurements of beam quality in the x-ray field demonstrate the stability of the kV-switching method. Phantom and in vivo experiments showed that images did not deviate from those of corresponding kV-constant scans. All performed experiments confirmed the capability of performing fast kV-switching scans on a clinically available C-arm CT system. More complex material decomposition tasks and postprocessing steps will be part of future investigations.

Indexed as

Radiation DosageAnimalsCalibrationContrast MediaFeasibility StudiesPhantoms, ImagingSwineTomography, X-Ray ComputedContrast Media

Identifiers

PMID27782692
PMCPMC5035311

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.