ArticleNature communications2016
Carbon nanotubes allow capture of krypton, barium and lead for multichannel biological X-ray fluorescence imaging.
Article in Nature communications, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed, 51 citations in OpenAlex.
- Near-Infrared Cocrystal Nanofluorophore with Enhanced Two-Photon Absorption Cross Sections.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- A Comprehensive Review on Filled Carbon Nanotubes: Synthesis, Properties and Applications.Chemical reviews · 2026Review
- Atomic-Scale Time-Resolved Imaging of Krypton Dimers, Chains and Transition to a One-Dimensional Gas.ACS nano · 2024Article
- Doped Graphene Quantum Dots as Biocompatible Radical Scavenging Agents.Antioxidants (Basel, Switzerland) · 2023Article
- Cytotoxicity of Carbon Nanotubes, Graphene, Fullerenes, and Dots.Nanomaterials (Basel, Switzerland) · 2023Review
- Spectroscopic Insights into the Influence of Filling Carbon Nanotubes with Atomic Nanowires for Photophysical and Photochemical Applications.ACS applied nano materials · 2023Article
- Towards routine 3D characterization of intact mesoscale samples by multi-scale and multimodal scanning X-ray tomography.Scientific reports · 2022Article
- Carbon nanotubes in biomedical applications: current status, promises, and challenges.Carbon letters · 2022Review
- The Role of Temperature on the Degree of End-Closing and Filling of Single-Walled Carbon Nanotubes.Nanomaterials (Basel, Switzerland) · 2021Article
- Applications of Pristine and Functionalized Carbon Nanotubes, Graphene, and Graphene Nanoribbons in Biomedicine.Nanomaterials (Basel, Switzerland) · 2021Review
- Applications of Filled Single-Walled Carbon Nanotubes: Progress, Challenges, and Perspectives.Nanomaterials (Basel, Switzerland) · 2021Review
- Article
- A Visual and Ratiometric Chemosensor Using Thiophene Functionalized Hydrazone for the Selective Sensing of PbJournal of fluorescence · 2021Article
- A label-free electrochemical biosensor based on magnetic biocomposites with DNAzyme and hybridization chain reaction dual signal amplification for the determination of PbMikrochimica acta · 2020Article
- Customisable X-ray fluorescence photodetector with submicron sensitivity using a ring array of silicon p-i-n diodes.Scientific reports · 2018Article
- Graftable SCoMPIs enable the labeling and X-ray fluorescence imaging of proteins.Chemical science · 2018Article
- Article
Corrections and comments
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Authors and funding
13 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The desire to study biology in situ has been aided by many imaging techniques. Among these, X-ray fluorescence (XRF) mapping permits observation of elemental distributions in a multichannel manner. However, XRF imaging is underused, in part, because of the difficulty in interpreting maps without an underlying cellular 'blueprint'; this could be supplied using contrast agents. Carbon nanotubes (CNTs) can be filled with a wide range of inorganic materials, and thus can be used as 'contrast agents' if biologically absent elements are encapsulated. Here we show that sealed single-walled CNTs filled with lead, barium and even krypton can be produced, and externally decorated with peptides to provide affinity for sub-cellular targets. The agents are able to highlight specific organelles in multiplexed XRF mapping, and are, in principle, a general and versatile tool for this, and other modes of biological imaging.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.