Evidence map›Paper›PMID 27782158›Full record

ArticleScientific reports2016

Analyses of RNA-Seq and sRNA-Seq data reveal a complex network of anti-viral defense in TCV-infected Arabidopsis thaliana.

Chao Wu, Xinyue Li, Song Guo, Sek-Man Wong

Abstract read
In one paragraph

Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. SNc Nuclease GenesInternational journal of molecular sciences · 2026
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  2. Article
  3. Article
  4. Impact of Exogenous dsRNA on miRNA Composition inPlants (Basel, Switzerland) · 2024
    Article
  5. EnhancingFrontiers in plant science · 2024
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. iTRAQ-Based Proteomic Analysis of Watermelon Fruits in Response toInternational journal of molecular sciences · 2020
    Article
  11. Article
  12. A Regulatory Network for miR156-SPL Module inInternational journal of molecular sciences · 2019
    Review
  13. Antiviral ARGONAUTEs AgainstPlant physiology · 2019
    Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Chao WuNUS Graduate School for Integrative Sciences and Engineering, National University of Singapore, Singapore.
Xinyue LiVishuo Biomedical Pte Ltd, Science Park II, Singapore.
Song GuoDepartment of Biological Sciences, National University of Singapore, Singapore.
Sek-Man WongNUS Graduate School for Integrative Sciences and Engineering, National University of Singapore, Singapore.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In order to identify specific plant anti-viral genes related to the miRNA regulatory pathway, RNA-Seq and sRNA-Seq were performed using Arabidopsis WT and dcl1-9 mutant line. A total of 5,204 DEGs were identified in TCV-infected WT plants. In contrast, only 595 DEGs were obtained in the infected dcl1-9 mutant plants. GO enrichment analysis of the shared DEGs and dcl1-9 unique DEGs showed that a wide range of biological processes were affected in the infected WT plants. In addition, miRNAs displayed different patterns between mock and infected WT plants. This is the first global view of dcl1-9 transcriptome which provides TCV responsive miRNAs data. In conclusion, our results indicated the significance of DCL1 and suggested that PPR genes may play an important role in plant anti-viral defense.

Indexed as

ArabidopsisGene Expression Regulation, PlantMicroRNAsRNA, PlantCarmovirusPlant DiseasesMicroRNAsRNA, Plant

Identifiers

PMID27782158
PMCPMC5080594

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.