ArticleScientific reports2016
Terahertz reflectometry imaging for low and high grade gliomas.
Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
30 citing papers in PubMed.
- Terahertz-based prognostic framework for glioma: from spectral features to patient-level prognostic assessment.npj biomedical innovations · 2026Article
- Synergistic terahertz platforms for precision oncology.Theranostics · 2026Review
- Review
- Rapid diagnosis of TERT promoter mutation using Terahertz absorption spectroscopy in glioblastoma.Scientific reports · 2025Article
- A new horizon for neuroscience: terahertz biotechnology in brain research.Neural regeneration research · 2025Article
- Article
- THz-Wave Absorption Properties of Organic-Inorganic Hybrid Perovskite Materials: A New Candidate for THz Sensors.Small science · 2024Article
- Exploring the impedance-matching effect in terahertz reflection imaging of skin tissue.Biomedical optics express · 2024Article
- Biomedical application of terahertz imaging technology: a narrative review.Quantitative imaging in medicine and surgery · 2023Review
- Review
- Triage ofBiomedical optics express · 2023Article
- Measurement of tissue optical properties in a wide spectral range: a review [Invited].Biomedical optics express · 2023Review
- Measurement and Modeling of the Optical Properties of Adipose Tissue in the Terahertz Range: Aspects of Disease Diagnosis.Diagnostics (Basel, Switzerland) · 2022Article
- Terahertz Spectral Properties of PEO-Based Anti-Adhesion Films Cross-Linked by Electron Beam Irradiation.Polymers · 2022Article
- Supervised machine learning for automatic classification of in vivo scald and contact burn injuries using the terahertz Portable Handheld Spectral Reflection (PHASR) Scanner.Scientific reports · 2022Article
- Temperature dependent terahertz spectroscopy and imaging of orthotopic brain gliomas in mouse models.Biomedical optics express · 2022Article
- Advances of terahertz technology in neuroscience: Current status and a future perspective.iScience · 2021Review
- Terahertz dielectric spectroscopy and solid immersion microscopy ofBiomedical optics express · 2021Article
- THz Sensing of Human Skin: A Review of Skin Modeling Approaches.Sensors (Basel, Switzerland) · 2021Review
- Terahertz dielectric spectroscopy of human brain gliomas and intact tissuesBiomedical optics express · 2021Article
Corrections and comments
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Authors and funding
15 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Gross total resection (GTR) of glioma is critical for improving the survival rate of glioma patients. One of the greatest challenges for achieving GTR is the difficulty in discriminating low grade tumor or peritumor regions that have an intact blood brain barrier (BBB) from normal brain tissues and delineating glioma margins during surgery. Here we present a highly sensitive, label-free terahertz reflectometry imaging (TRI) that overcomes current key limitations for intraoperative detection of World Health Organization (WHO) grade II (low grade), and grade III and IV (high grade) gliomas. We demonstrate that TRI provides tumor discrimination and delineation of tumor margins in brain tissues with high sensitivity on the basis of Hematoxylin and eosin (H&E) stained image. TRI may help neurosurgeons to remove gliomas completely by providing visualization of tumor margins in WHO grade II, III, and IV gliomas without contrast agents, and hence, improve patient outcomes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.