ArticlePediatric transplantation2016
Mass cytometry reveals a distinct immunoprofile of operational tolerance in pediatric liver transplantation.
Article in Pediatric transplantation, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed.
- High-dimensional profiling of pediatric immune responses to solid organ transplantation.Cell reports. Medicine · 2023Article
- Revisiting transplant immunology through the lens of single-cell technologies.Seminars in immunopathology · 2023Review
- Clinical characteristics of immune tolerance after pediatric liver transplantation.BMC surgery · 2022Article
- Machine perfusion of the liver: applications in transplantation and beyond.Nature reviews. Gastroenterology & hepatology · 2022Review
- Prediction of tumor recurrence by distinct immunoprofiles in liver transplant patients based on mass cytometry.American journal of cancer research · 2022Article
- Strategies for Liver Transplantation Tolerance.International journal of molecular sciences · 2021Review
- Harnessing Mechanisms of Immune Tolerance to Improve Outcomes in Solid Organ Transplantation: A Review.Frontiers in immunology · 2021Review
- Understanding, predicting and achieving liver transplant tolerance: from bench to bedside.Nature reviews. Gastroenterology & hepatology · 2020Review
- Progress and applications of mass cytometry in sketching immune landscapes.Clinical and translational medicine · 2020Review
- Regulatory T cells in solid organ transplantation.Clinical & translational immunology · 2020Review
- Transplant Tolerance Induction: Insights From the Liver.Frontiers in immunology · 2020Review
- Mass Cytometry for the Assessment of Immune Reconstitution After Hematopoietic Stem Cell Transplantation.Frontiers in immunology · 2018Review
- Immunological Prediction of Cytomegalovirus (CMV) Replication Risk in Solid Organ Transplantation Recipients: Approaches for Regulating the Targeted Anti-CMV Prevention Strategies.Infection & chemotherapy · 2017Review
- Applying Mass Cytometry to the Analysis of Lymphoid Populations in Transplantation.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2017Review
- Combining Flow and Mass Cytometry in the Search for Biomarkers in Chronic Graft-versus-Host Disease.Frontiers in immunology · 2017Article
- Operational Tolerance after Liver Transplantation: First Report from India.Journal of clinical and experimental hepatologyArticle
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
Long-term IS in transplant patients has significant morbidity, poorer quality of life, and substantial economic costs. TOL, defined as graft acceptance without functional impairment in the absence of IS, has been achieved in some pediatric LT recipients. Using mass cytometry, peripheral blood immunotyping was performed to characterize differences between tolerant patients and patients who are stable on single-agent IS. Single-cell mass cytometry was performed using blood samples from a single-center pediatric LT population of operationally tolerant patients to comprehensively characterize the immune cell populations in the tolerant state compared with patients on chronic low-dose IS. Specific T-cell populations of interest were confirmed by flow cytometry. This high-dimensional phenotypic analysis revealed distinct immunoprofiles between transplant populations as well as a CD4
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