Evidence map›Paper›PMID 27781180›Full record

ArticlePeerJ2016

A pilot study examining the effects of low-volume high-intensity interval training and continuous low to moderate intensity training on quality of life, functional capacity and cardiovascular risk factors in cancer survivors.

Kellie Toohey, Kate L Pumpa, Leonard Arnolda, Julie Cooke, Desmond Yip, Paul S Craft, Stuart Semple

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in PeerJ, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03308734 (Effects of 6 Week Reduced Exertion High Intensity Interval Training Protocol in Patients With Prostate Cancer), which is not on this map. Cited by 25 papers, 11 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 11 pooled it
12.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03308734 nawithdrawnnot on this mapstarted 2019, after this paper: background citation

Effects of 6 Week Reduced Exertion High Intensity Interval Training Protocol in Patients With Prostate Cancer

TypeinterventionalSponsorUniversity of BathRan2019 to 2020Enrolled0ConditionsProstate CancerArmsReduced-Exertion High-Intensity Interval Training
3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 11 syntheses or guidelines pooled it, 58 citations in OpenAlex.

  1. Pooled it
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  5. High-intensity interval training effects in cardiorespiratory fitness of lung cancer survivors: a systematic review and meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022
    Pooled it
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  10. Barriers and facilitators of exercise experienced by cancer survivors: a mixed methods systematic review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2018
    Pooled it
  11. Pooled it
  12. Exercise and cancer-related lymphedema in the lower limbs-a randomized cross-over trial on high-intensity interval training (HIIT) with and without compression garments.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
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  17. Article
  18. Net Heart Rate for Estimating Oxygen Consumption in Active Adults.Journal of functional morphology and kinesiology · 2024
    Article
  19. Article
  20. The effects of prehabilitation on body composition in patients undergoing multimodal therapy for esophageal cancer.Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Kellie TooheyDiscipline of Sport and Exercise Science/Faculty of Health, University of Canberra, Canberra, ACT, Australia; Research Institute for Sport and Exercise, University of Canberra, Canberra, ACT, Australia.
Kate L PumpaDiscipline of Sport and Exercise Science/Faculty of Health, University of Canberra, Canberra, ACT, Australia; Research Institute for Sport and Exercise, University of Canberra, Canberra, ACT, Australia.
Leonard ArnoldaANU Medical School, Australian National University , Canberra , ACT , Australia.
Julie CookeDiscipline of Sport and Exercise Science/Faculty of Health, University of Canberra, Canberra, ACT, Australia; Research Institute for Sport and Exercise, University of Canberra, Canberra, ACT, Australia.
Desmond YipANU Medical School, Australian National University , Canberra , ACT , Australia.
Paul S CraftANU Medical School, Australian National University , Canberra , ACT , Australia.
Stuart SempleDiscipline of Sport and Exercise Science/Faculty of Health, University of Canberra, Canberra, ACT, Australia; Research Institute for Sport and Exercise, University of Canberra, Canberra, ACT, Australia.
University of Canberra · AUAustralian National University · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe aim of this study was to evaluate the effects of low-volume high-intensity interval training and continuous low to moderate intensity training on quality of life, functional capacity and cardiovascular disease risk factors in cancer survivors.

methodsCancer survivors within 24 months post-diagnosis were randomly assigned into the low-volume high-intensity interval training group (

resultsSignificant improvements (time) were observed for 13 of the 23 dependent variables (ES 0.05-0.61,

conclusionThese preliminary findings suggest that both interventions can induce improvements in quality of life, functional capacity and selected cardiovascular disease risk factors. The LVHIIT program was well tolerated by the participants and our results suggest that LVHIIT is the preferred modality to improve fitness (6MWT); it remains to be seen which intervention elicits the most clinically relevant outcomes for patients. A larger sample size with a control group is required to confirm the significance of these findings.

Indexed as

Cancer survivorsCardiovascular diseaseExerciseFunctional capacityHealthHigh-intensityModerate-intensityPhysical activityQuality of lifeTraining

Identifiers

PMID27781180
PMCPMC5075690
OpenAlexW2534244574

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.