Evidence map›Paper›PMID 27781091›Full record

ArticleF1000Research2016

Reduced neuronal size and mTOR pathway activity in the Mecp2 A140V Rett syndrome mouse model.

Sampathkumar Rangasamy, Shannon Olfers, Brittany Gerald, Alex Hilbert, Sean Svejda, Vinodh Narayanan

Open access · goldAbstract read
In one paragraph

Article in F1000Research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
1.8field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 40 citations in OpenAlex.

  1. Article
  2. Article
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  4. The function ofFrontiers in cellular neuroscience · 2024
    Review
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  6. Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Rett Syndrome andNeuropsychiatric disease and treatment · 2022
    Review
  12. Article
  13. Review
  14. Article
  15. Article
  16. Review
  17. Article
  18. Identification of hsa-miR-1275 as a Novel Biomarker TargetingMolecular therapy. Methods & clinical development · 2020
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Sampathkumar RangasamyNeurogenomics Division, Translational Genomics Research Institute, Phoenix, USA; Center for Rare Childhood Disorders, Translational Genomics Research Institute, Phoenix, USA.
Shannon OlfersBarrow Neurological Institute, St.Joseph's Hospital and Medical Center, Phoenix, USA.
Brittany GeraldNeurogenomics Division, Translational Genomics Research Institute, Phoenix, USA; Center for Rare Childhood Disorders, Translational Genomics Research Institute, Phoenix, USA; School of Life Sciences, Arizona State University, Tempe, USA.
Alex HilbertNeurogenomics Division, Translational Genomics Research Institute, Phoenix, USA; School of Life Sciences, Arizona State University, Tempe, USA.
Sean SvejdaNeurogenomics Division, Translational Genomics Research Institute, Phoenix, USA; Center for Rare Childhood Disorders, Translational Genomics Research Institute, Phoenix, USA.
Vinodh NarayananNeurogenomics Division, Translational Genomics Research Institute, Phoenix, USA; Center for Rare Childhood Disorders, Translational Genomics Research Institute, Phoenix, USA; Barrow Neurological Institute, St.Joseph's Hospital and Medical Center, Phoenix, USA; School of Life Sciences, Arizona State University, Tempe, USA.
Translational Genomics Research Institute · USBarrow Neurological Institute · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rett syndrome (RTT) is a neurodevelopmental disorder caused by mutation in the X-linked

Indexed as

Cerebellar granule neuronsHippocampal neuronal culturesIGF-1MECP2mTOR pathwayNeuronal nuclear sizeNeuronal soma sizeRett syndromeRictor

Identifiers

PMID27781091
PMCPMC5040159
OpenAlexW2507337557

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.