Evidence map›Paper›PMID 27781052›Full record

ReviewInterventional neurology2016

Arteriovenous Malformations in the Pediatric Population: Review of the Existing Literature.

Mohammad El-Ghanem, Tareq Kass-Hout, Omar Kass-Hout, Yazan J Alderazi, Krishna Amuluru, Fawaz Al-Mufti, Charles J Prestigiacomo, Chirag D Gandhi

Open access · bronzeAbstract readReview
In one paragraph

Review in Interventional neurology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 2 pooled it
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 2 syntheses or guidelines pooled it, 106 citations in OpenAlex.

  1. Stereotactic radiosurgery treatment of pediatric arteriovenous malformations: a PRISMA systematic review and meta-analysis.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2025
    Pooled it
  2. Pooled it
  3. Review
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  5. Article
  6. Article
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  10. Review
  11. Hypofractionated stereotactic radiotherapy in Spetzler Martin grades 4 and 5 arteriovenous malformations in the pediatric population: Is it a viable alternative?Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2024
    Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Arterial Spin Labeling for Pediatric Central Nervous System Diseases: Techniques and Clinical Applications.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2023
    Article
  17. Article
  18. Observational
  19. Single-center experience with endovascular treatment of cerebral arteriovenous malformations with intent to cure in pediatric patients.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2022
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Mohammad El-GhanemDepartment of Neurology, Pennsylvania State University, Hershey, Pa, N.Y., USA.
Tareq Kass-HoutDepartment of Neurosurgery and Neuroscience, Rutgers University School of Medicine, Newark, N.J, N.Y., USA; Division of Neuro-Endovascular Surgery, Department of Surgery, Rochester Regional Health System, Rochester, N.Y., USA.
Omar Kass-HoutDepartment of Neurology, Emory University School of Medicine, Atlanta, Va, N.Y., USA.
Yazan J AlderaziDepartment of Neurosurgery and Neuroscience, Rutgers University School of Medicine, Newark, N.J, N.Y., USA.
Krishna AmuluruDepartment of Neurosurgery and Neuroscience, Rutgers University School of Medicine, Newark, N.J, N.Y., USA.
Fawaz Al-MuftiDepartment of Neurosurgery and Neuroscience, Rutgers University School of Medicine, Newark, N.J, N.Y., USA.
Charles J PrestigiacomoDepartment of Neurosurgery and Neuroscience, Rutgers University School of Medicine, Newark, N.J, N.Y., USA.
Chirag D GandhiDepartment of Neurosurgery and Neuroscience, Rutgers University School of Medicine, Newark, N.J, N.Y., USA.
Rutgers, The State University of New Jersey · USEmory University · USPennsylvania State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Arteriovenous malformations (AVMs) in the pediatric population are relatively rare but reportedly carry a higher rate of rupture than in adults. This could be due to the fact that most pediatric AVMs are only detected after rupture. We aimed to review the current literature regarding the natural history and the clinical outcome after multimodality AVM treatment in the pediatric population, as optimal management for pediatric AVMs remains controversial. A multidisciplinary approach using multimodality therapy if needed has been proved to be beneficial in approaching these lesions in all age groups. Microsurgical resection remains the gold standard for the treatment of all accessible pediatric AVMs. Embolization and radiosurgery should be considered as an adjunctive therapy. Embolization provides a useful adjunct therapy to microsurgery by preventing significant blood loss and to radiosurgery by decreasing the volume of the AVM. Radiosurgery has been described to provide an alternative treatment approach in certain circumstances either as a primary or adjuvant therapy.

Indexed as

Arteriovenous malformationsEndovascular embolizationMicrosurgeryPediatricsStereotactic radiosurgery

Identifiers

PMID27781052
PMCPMC5075815
OpenAlexW2515502200

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.