Evidence map›Paper›PMID 27780836›Full record

ArticleCirculation. Heart failure2016

Variation in Hospital Use and Outcomes Associated With Pulmonary Artery Catheterization in Heart Failure in the United States.

Rohan Khera, Ambarish Pandey, Nilay Kumar, Rajeev Singh, Shah Bano, Harsh Golwala, Dharam J Kumbhani, Saket Girotra, Gregg C Fonarow

Open access · bronzeAbstract read
In one paragraph

Article in Circulation. Heart failure, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 52 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Rohan KheraFrom the Division of Cardiology, University of Texas Southwestern Medical Center, Dallas (R.K., A.P., S.B., D.J.K.); Cambridge Health Alliance Hospital, Harvard Medical School, Boston, MA (N.K.); Division of Cardiology, Indiana University School of Medicine, Indianapolis (R.S.); Division of Cardiovascular Medicine, Brigham and Women's Hospital, Boston, MA (H.G.); Division of Cardiovascular Medicine, Department of Internal Medicine, University of Iowa Carver College of Medicine Iowa City (S.G.); and Ahmanson-University of California at Los Angeles Cardiomyopathy Center, Ronald Reagan-University of California at Los Angeles Medical Center (G.C.F.).
Ambarish PandeyFrom the Division of Cardiology, University of Texas Southwestern Medical Center, Dallas (R.K., A.P., S.B., D.J.K.); Cambridge Health Alliance Hospital, Harvard Medical School, Boston, MA (N.K.); Division of Cardiology, Indiana University School of Medicine, Indianapolis (R.S.); Division of Cardiovascular Medicine, Brigham and Women's Hospital, Boston, MA (H.G.); Division of Cardiovascular Medicine, Department of Internal Medicine, University of Iowa Carver College of Medicine Iowa City (S.G.); and Ahmanson-University of California at Los Angeles Cardiomyopathy Center, Ronald Reagan-University of California at Los Angeles Medical Center (G.C.F.).
Nilay KumarFrom the Division of Cardiology, University of Texas Southwestern Medical Center, Dallas (R.K., A.P., S.B., D.J.K.); Cambridge Health Alliance Hospital, Harvard Medical School, Boston, MA (N.K.); Division of Cardiology, Indiana University School of Medicine, Indianapolis (R.S.); Division of Cardiovascular Medicine, Brigham and Women's Hospital, Boston, MA (H.G.); Division of Cardiovascular Medicine, Department of Internal Medicine, University of Iowa Carver College of Medicine Iowa City (S.G.); and Ahmanson-University of California at Los Angeles Cardiomyopathy Center, Ronald Reagan-University of California at Los Angeles Medical Center (G.C.F.).
Rajeev SinghFrom the Division of Cardiology, University of Texas Southwestern Medical Center, Dallas (R.K., A.P., S.B., D.J.K.); Cambridge Health Alliance Hospital, Harvard Medical School, Boston, MA (N.K.); Division of Cardiology, Indiana University School of Medicine, Indianapolis (R.S.); Division of Cardiovascular Medicine, Brigham and Women's Hospital, Boston, MA (H.G.); Division of Cardiovascular Medicine, Department of Internal Medicine, University of Iowa Carver College of Medicine Iowa City (S.G.); and Ahmanson-University of California at Los Angeles Cardiomyopathy Center, Ronald Reagan-University of California at Los Angeles Medical Center (G.C.F.).
Shah BanoFrom the Division of Cardiology, University of Texas Southwestern Medical Center, Dallas (R.K., A.P., S.B., D.J.K.); Cambridge Health Alliance Hospital, Harvard Medical School, Boston, MA (N.K.); Division of Cardiology, Indiana University School of Medicine, Indianapolis (R.S.); Division of Cardiovascular Medicine, Brigham and Women's Hospital, Boston, MA (H.G.); Division of Cardiovascular Medicine, Department of Internal Medicine, University of Iowa Carver College of Medicine Iowa City (S.G.); and Ahmanson-University of California at Los Angeles Cardiomyopathy Center, Ronald Reagan-University of California at Los Angeles Medical Center (G.C.F.).
Harsh GolwalaFrom the Division of Cardiology, University of Texas Southwestern Medical Center, Dallas (R.K., A.P., S.B., D.J.K.); Cambridge Health Alliance Hospital, Harvard Medical School, Boston, MA (N.K.); Division of Cardiology, Indiana University School of Medicine, Indianapolis (R.S.); Division of Cardiovascular Medicine, Brigham and Women's Hospital, Boston, MA (H.G.); Division of Cardiovascular Medicine, Department of Internal Medicine, University of Iowa Carver College of Medicine Iowa City (S.G.); and Ahmanson-University of California at Los Angeles Cardiomyopathy Center, Ronald Reagan-University of California at Los Angeles Medical Center (G.C.F.).
Dharam J KumbhaniFrom the Division of Cardiology, University of Texas Southwestern Medical Center, Dallas (R.K., A.P., S.B., D.J.K.); Cambridge Health Alliance Hospital, Harvard Medical School, Boston, MA (N.K.); Division of Cardiology, Indiana University School of Medicine, Indianapolis (R.S.); Division of Cardiovascular Medicine, Brigham and Women's Hospital, Boston, MA (H.G.); Division of Cardiovascular Medicine, Department of Internal Medicine, University of Iowa Carver College of Medicine Iowa City (S.G.); and Ahmanson-University of California at Los Angeles Cardiomyopathy Center, Ronald Reagan-University of California at Los Angeles Medical Center (G.C.F.).
Saket GirotraFrom the Division of Cardiology, University of Texas Southwestern Medical Center, Dallas (R.K., A.P., S.B., D.J.K.); Cambridge Health Alliance Hospital, Harvard Medical School, Boston, MA (N.K.); Division of Cardiology, Indiana University School of Medicine, Indianapolis (R.S.); Division of Cardiovascular Medicine, Brigham and Women's Hospital, Boston, MA (H.G.); Division of Cardiovascular Medicine, Department of Internal Medicine, University of Iowa Carver College of Medicine Iowa City (S.G.); and Ahmanson-University of California at Los Angeles Cardiomyopathy Center, Ronald Reagan-University of California at Los Angeles Medical Center (G.C.F.).
Gregg C FonarowFrom the Division of Cardiology, University of Texas Southwestern Medical Center, Dallas (R.K., A.P., S.B., D.J.K.); Cambridge Health Alliance Hospital, Harvard Medical School, Boston, MA (N.K.); Division of Cardiology, Indiana University School of Medicine, Indianapolis (R.S.); Division of Cardiovascular Medicine, Brigham and Women's Hospital, Boston, MA (H.G.); Division of Cardiovascular Medicine, Department of Internal Medicine, University of Iowa Carver College of Medicine Iowa City (S.G.); and Ahmanson-University of California at Los Angeles Cardiomyopathy Center, Ronald Reagan-University of California at Los Angeles Medical Center (G.C.F.). gfonarow@mednet.ucla.edu.
Brigham and Women's Hospital · USIndiana University – Purdue University Indianapolis · USCambridge Health Alliance · USUniversity of Iowa · US

Funding

UT Southwestern Center for Translational Medicine (UL1/KL2/TL1)UL1TR001105 · NCATS · UT SOUTHWESTERN MEDICAL CENTER · PI TOTO, ROBERT DANIEL · 2013 to 2017
$24.5M
Training in Cardiovascular ResearchT32HL125247 · NHLBI · UT SOUTHWESTERN MEDICAL CENTER · PI JOSEPH A HILL · 2015 to 2026
$4.3M
Post-Resuscitation Care and Survival After In-hospital Cardiac ArrestK08HL122527 · NHLBI · UNIVERSITY OF IOWA · PI GIROTRA, SAKET · 2014 to 2018
$731k
ACTION - A CHF Trial Investigating Outcomes of ExerciseU01HL068980 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI FONAROW, GREGG C · 2002 to 2006
$709k
NCATS NIH HHS UL1 TR001105NHLBI NIH HHS K08 HL122527NHLBI NIH HHS T32 HL125247NHLBI NIH HHS U01 HL068980
6 · The paper itself

Abstract

backgroundThere has been an increase in the use of pulmonary artery (PA) catheters in heart failure (HF) in the United States in recent years. However, patterns of hospital use and trends in patient outcomes are not known. METHODS AND

resultsIn the National Inpatient Sample 2001 to 2012, using International Classification of Diseases-Ninth Revision codes, we identified 11 888 525 adult (≥18 years) HF hospitalizations nationally, of which an estimated 75 209 (SE 0.6%) received a PA catheter. In 2001, the number of hospitals with ≥1 PA catheterization was 1753, decreasing to 1183 in 2011. The mean PA catheter use per hospital trended from 4.9 per year in 2001 (limits 1-133) to 3.8 per year in 2007 (limits 1-46), but increased to 5.5 per year in 2011 (limits 1-70). During 2001 to 2006, PA catheterization declined across hospitals; however, in 2007 to 2012, there was a disproportionate increase at hospitals with large bedsize, teaching programs, and advanced HF capabilities. The overall in-hospital mortality with PA catheter use was higher than without PA catheter use (13.1% versus 3.4%; P<0.0001); however, in propensity-matched analysis, differences in mortality between these groups have attenuated over time-risk-adjusted odds ratio for mortality for PA catheterization, 1.66 (95% confidence interval, 1.60-1.74) in 2001 to 2003 down to 1.04 (95% confidence interval, 0.97-1.12) in 2010 to 2012.

conclusionsThere is substantial hospital-level variability in PA catheterization in HF along with increasing volume at fewer hospitals over-represented by large, academic hospitals with advanced HF capabilities. This is accompanied by a decline in excess mortality associated with PA catheterization.

Indexed as

Hospital MortalityPractice Patterns, Physicians'AgedArrhythmias, CardiacCase-Control StudiesCatheterization, Swan-GanzCerebrovascular DisordersCoronary Artery DiseaseDatabases, FactualDisease ManagementFemaleHeart ArrestHeart FailureHospitalsHumansLength of Staycatheterizationheart failurehospitalizationInternational Classification of Diseasespulmonary artery

Identifiers

PMID27780836
PMCPMC5123800
OpenAlexW2537119494

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.