Evidence map›Paper›PMID 27780483›Full record

ArticleEpidemiology and infection2017

A population-based longitudinal study of Clostridium difficile infection-related hospitalization in mid-age and older Australians.

Y Chen, K Glass, B Liu, T V Riley, R Korda, M D Kirk

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Epidemiology and infection, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. The Global Burden ofInfectious disease reports · 2025
    Review
  2. Guideline for the Management ofJournal of clinical oncology : official journal of the American Society of Clinical Oncology · 2018
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Y ChenResearch School of Population Health,Australian National University,Canberra,Australia.
K GlassResearch School of Population Health,Australian National University,Canberra,Australia.
B LiuSchool of Public Health and Community Medicine,University of New South Wales,Sydney,Australia.
T V RileyMicrobiology & Immunology, University of Western Australia, and Department of Microbiology Path West Laboratory Medicine,Queen Elizabeth II Medical Centre,Nedlands,Australia.
R KordaResearch School of Population Health,Australian National University,Canberra,Australia.
M D KirkResearch School of Population Health,Australian National University,Canberra,Australia.
Australian National University · AUQueen Elizabeth II Medical Centre · AUUNSW Sydney · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Clostridium difficile is the principal cause of infectious diarrhoea in hospitalized patients. We investigated the incidence and risk factors for hospitalization due to C. difficile infection (CDI) in older Australians. We linked data from a population-based prospective cohort study (the 45 and Up Study) of 266 922 adults aged ⩾45 years recruited in New South Wales, Australia to hospitalization and death records for 2006-2012. We estimated the incidence of CDI hospitalization and calculated days in hospital and costs per hospitalization. We also estimated hazard ratios (HR) for CDI hospitalization using Cox regression with age as the underlying time variable. Over a total follow-up of 1 126 708 person-years, 187 adults had an incident CDI hospitalization. The crude incidence of CDI hospitalization was 16·6/100 000 person-years, with a median hospital stay of 6 days, and a median cost of AUD 6102 per admission. Incidence increased with age and year of follow-up, with a threefold increase for 2009-2012. After adjustment, CDI hospitalization rates were significantly lower in males than females (adjusted HR 0·6, 95% confidence interval 0·4-0·7). CDI hospitalization rates increased significantly over 2009-2012. There is a need to better understand the increasing risk of CDI hospitalization in women.

Indexed as

HospitalizationAgedAged, 80 and overAge FactorsClostridioides difficileClostridium InfectionsDiarrheaFemaleHealth Care CostsHumansIncidenceLength of StayLongitudinal StudiesMaleMiddle AgedNew South WalesClostridium difficileepidemiology

Identifiers

PMID27780483
PMCPMC9507632
OpenAlexW2539479962

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.