Evidence map›Paper›PMID 27780336›Full record

Trial reportThe Journal of clinical psychiatry2017

Improving Physical Health in Patients With Chronic Mental Disorders: Twelve-Month Results From a Randomized Controlled Collaborative Care Trial.

Amy M Kilbourne, Michelle M Barbaresso, Zongshan Lai, Kristina M Nord, Margretta Bramlet, David E Goodrich, Edward P Post, Daniel Almirall, Mark S Bauer

2 registry-linked trialsOpen access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in The Journal of clinical psychiatry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 23 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 3 pooled it
5.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01244854 nacompletednot on this map

Life Goals Behavioral Change to Improve Outcomes for Veterans With SMI

TypeinterventionalSponsorVA Office of Research and DevelopmentRan2010 to 2015Enrolled55ConditionsBipolar Disorder, Schizophrenia, Major Depressive Disorder, Chronic Affective DisordersArmsLife Goals Collaborative Care
NCT01487668 nacompletednot on this map

Life Goals Collaborative Care to Improve Health Outcomes in Mental Disorders

TypeinterventionalSponsorVA Office of Research and DevelopmentRan2011 to 2015Enrolled304ConditionsBipolar Disorder, Schizophrenia, Major Depressive Disorder, Schizoaffective DisorderArmsLife Goals Collaborative Care
3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 3 syntheses or guidelines pooled it, 38 citations in OpenAlex.

  1. Collaborative care approaches for people with severe mental illness.The Cochrane database of systematic reviews · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Amy M KilbourneVA Center for Clinical Management Research, 2215 Fuller Rd, Mailstop 152, Ann Arbor, MI 48105. amykilbo@umich.edu.
Michelle M BarbaressoVA Center for Clinical Management Research, Ann Arbor, Michigan, USA.
Zongshan LaiVA Center for Clinical Management Research, Ann Arbor, Michigan, USA.
Kristina M NordVA Center for Clinical Management Research, Ann Arbor, Michigan, USA.
Margretta BramletVA Center for Clinical Management Research, Ann Arbor, Michigan, USA.
David E GoodrichVA Center for Clinical Management Research, Ann Arbor, Michigan, USA.
Edward P PostVA Center for Clinical Management Research, Ann Arbor, Michigan, USA.
Daniel AlmirallInstitute for Social Research, University of Michigan, Ann Arbor, Michigan, USA.
Mark S BauerVA Center for Healthcare Organization and Implementation Research, Boston, Massachusetts, USA.
University of Michigan–Ann Arbor · USVA Center for Clinical Management Research · USHarvard University · US

Funding

Pilot, Mentoring, and Professional Development CoreP50DA039838 · NIDA · PENNSYLVANIA STATE UNIVERSITY, THE · PI LI, RUNZE · 2015 to 2019
$13.9M
Novel Methods for Intensive Longitudinal Data in SMART Studies of Drug Abuse and HIVR01DA039901 · NIDA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI ALMIRALL, DANIEL, NAHUM-SHANI, INBAL BILLIE · 2015 to 2024
$5.4M
Life Goals Collaborative Care to Improve Health Outcomes in Mental DisordersI01HX000551 · VA · VETERANS HEALTH ADMINISTRATION · PI KILBOURNE, AMY M · 2013 to 2013
–
HSRD VA I01 HX000551NIDA NIH HHS P50 DA039838NIDA NIH HHS R01 DA039901
6 · The paper itself

Abstract

objectivePersons with chronic mental disorders are disproportionately burdened with physical health conditions. We determined whether Life Goals Collaborative Care compared to usual care improves physical health in patients with mental disorders within 12 months.

methodsThis single-blind randomized controlled effectiveness study of a collaborative care model was conducted at a midwestern Veterans Affairs urban outpatient mental health clinic. Patients (N = 293 out of 474 eligible approached) with an ICD-9-CM diagnosis of schizophrenia, bipolar disorder, or major depressive disorder and at least 1 cardiovascular disease risk factor provided informed consent and were randomized (February 24, 2010, to April 29, 2015) to Life Goals (n = 146) or usual care (n = 147). A total of 287 completed baseline assessments, and 245 completed 12-month follow-up assessments. Life Goals included 5 weekly sessions that provided semistructured guidance on managing physical and mental health symptoms through healthy behavior changes, augmented by ongoing care coordination. The primary outcome was change in physical health-related quality of life score (Veterans RAND 12-item Short Form Health Survey [VR-12] physical health component score). Secondary outcomes included control of cardiovascular risk factors from baseline to 12 months (blood pressure, lipids, weight), mental health-related quality of life, and mental health symptoms.

resultsAmong patients completing baseline and 12-month outcomes assessments (N = 245), the mean age was 55.3 years (SD = 10.8; range, 25-78 years), and 15.4% were female. Intent-to-treat analysis revealed that compared to those in usual care, patients randomized to Life Goals had slightly increased VR-12 physical health scores (coefficient = 3.21; P = .01).

conclusionsPatients with chronic mental disorders and cardiovascular disease risk who received Life Goals had improved physical health-related quality of life.

trial registrationClinicalTrials.gov identifiers: NCT01487668 and NCT01244854.

Indexed as

ExerciseHealth StatusInterdisciplinary CommunicationIntersectoral CollaborationAdultAgedAmbulatory Care FacilitiesCardiovascular DiseasesChronic DiseaseComorbidityFemaleHumansMaleMental DisordersMiddle AgedOutcome and Process Assessment, Health Care

Identifiers

PMID27780336
PMCPMC5272777
OpenAlexW2532294672

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.