Evidence map›Paper›PMID 27780201›Full record

ArticlePLoS neglected tropical diseases2016

Environmental Nontuberculous Mycobacteria in the Hawaiian Islands.

Jennifer R Honda, Nabeeh A Hasan, Rebecca M Davidson, Myra D Williams, L Elaine Epperson, Paul R Reynolds, Terry Smith, Elena Iakhiaeva, Matthew J Bankowski, Richard J Wallace and 3 more

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in PLoS neglected tropical diseases, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 58 papers.

0numbers the graph read from it
0cells of the map it votes in
58citing papers in PubMed
6.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

58 citing papers in PubMed, 82 citations in OpenAlex.

  1. Novel Hawai'i and Pacific Island circulating clusters ofApplied and environmental microbiology · 2026
    Article
  2. Documenting Environmentally Acquired Mycobacterium intracellulare subsp. chimaera Pulmonary Disease Soon After Bronchiectasis Onset.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2026
    Article
  3. Journal of bacteriology · 2026
    Review
  4. Understanding recurrence inJournal of clinical microbiology · 2026
    Review
  5. Infection control and hospital epidemiology · 2026
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Journal of clinical tuberculosis and other mycobacterial diseases · 2024
    Article
  11. Article
  12. Genomic epidemiology ofERJ open research · 2024
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Molecular Epidemiologic Investigation ofAnnals of the American Thoracic Society · 2023
    Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 1 country.

Jennifer R HondaDivision of Pulmonary Sciences and Critical Care Medicine, University of Colorado Denver, Anschutz Medical Campus, Aurora, Colorado, United States Of America.
Nabeeh A HasanNational Jewish Health, Denver, Colorado, United States Of America.
Rebecca M DavidsonNational Jewish Health, Denver, Colorado, United States Of America.
Myra D WilliamsVirginia Tech, Blacksburg, Virginia, United States Of America.
L Elaine EppersonNational Jewish Health, Denver, Colorado, United States Of America.
Paul R ReynoldsNational Jewish Health, Denver, Colorado, United States Of America.
Terry SmithVirginia Tech, Blacksburg, Virginia, United States Of America.
Elena IakhiaevaVirginia Tech, Blacksburg, Virginia, United States Of America.
Matthew J BankowskiDiagnostic Laboratory Services Inc., Aiea, Hawai'i, United States Of America.
Richard J WallaceUniversity of Texas Health Science Center, Tyler, Texas, United States Of America.
Edward D ChanDivision of Pulmonary Sciences and Critical Care Medicine, University of Colorado Denver, Anschutz Medical Campus, Aurora, Colorado, United States Of America.
Joseph O FalkinhamVirginia Tech, Blacksburg, Virginia, United States Of America.
Michael StrongDivision of Pulmonary Sciences and Critical Care Medicine, University of Colorado Denver, Anschutz Medical Campus, Aurora, Colorado, United States Of America.
National Jewish Health · USVirginia Tech · USUniversity of Colorado Denver · USThe University of Texas Health Science Center at Tyler · USUniversity of Hawaiʻi at Mānoa · US

Funding

Computational Bioscience Program Training GrantT15LM009451 · NLM · UNIVERSITY OF COLORADO DENVER · PI Katherina Kechris-Mays, Arjun Krishnan · 2007 to 2026
$11.7M
NLM NIH HHS T15 LM009451
6 · The paper itself

Abstract

Lung disease caused by nontuberculous mycobacteria (NTM) is an emerging infectious disease of global significance. Epidemiologic studies have shown the Hawaiian Islands have the highest prevalence of NTM lung infections in the United States. However, potential environmental reservoirs and species diversity have not been characterized. In this cross-sectional study, we describe molecular and phylogenetic comparisons of NTM isolated from 172 household plumbing biofilms and soil samples from 62 non-patient households and 15 respiratory specimens. Although non-uniform geographic sampling and availability of patient information were limitations, Mycobacterium chimaera was found to be the dominant species in both environmental and respiratory specimens. In contrast to previous studies from the continental U.S., no Mycobacterium avium was identified. Mycobacterium intracellulare was found only in respiratory specimens and a soil sample. We conclude that Hawai'i's household water sources contain a unique composition of Mycobacterium avium complex (MAC), increasing our appreciation of NTM organisms of pulmonary importance in tropical environments.

Indexed as

Soil MicrobiologyBiofilmsCross-Sectional StudiesHawaiiHousingHumansMycobacterium Infections, NontuberculousNontuberculous MycobacteriaPhylogeny

Identifiers

PMID27780201
PMCPMC5079566
OpenAlexW2533738645

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.