Evidence map›Paper›PMID 27780176›Full record

ArticlePain2016

A population-based study of quantitative sensory testing in adolescents with and without chronic pain.

See Wan Tham, Tonya M Palermo, Amy Lewandowski Holley, Chuan Zhou, Audun Stubhaug, Anne-Sofie Furberg, Christopher Sivert Nielsen

Abstract read
In one paragraph

Article in Pain, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  12. A multidimensional appraisal of early menstrual pain experience.American journal of obstetrics and gynecology · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

See Wan ThamDepartment of Anesthesiology & Pain Medicine, University of Washington School of Medicine, Seattle, WA, USA.
Tonya M PalermoDepartment of Anesthesiology & Pain Medicine, University of Washington School of Medicine, Seattle, WA, USA.
Amy Lewandowski HolleyInstitute of Development and Disability, Oregon Health & Science University, Portland, OR, USA.
Chuan ZhouSeattle Children's Research Institute, WA, USA.
Audun StubhaugDepartment of Pain Management and Research, Oslo University Hospital, Oslo, Norway.
Anne-Sofie FurbergDepartment of Community Medicine, The Arctic University of Norway, Tromsø, Norway.
Christopher Sivert NielsenDepartment of Pain Management and Research, Oslo University Hospital, Oslo, Norway.

Funding

Anesthesiology & Perioperative Medicine Training GrantT32GM086270 · NIGMS · UNIVERSITY OF WASHINGTON · PI Tonya M Palermo · 2009 to 2026
$4.3M
NIGMS NIH HHS T32 GM086270
6 · The paper itself

Abstract

Quantitative sensory testing (QST) has been used to characterize pain sensitivity in individuals with and without pain conditions. Research remains limited in pediatric populations, hindering the ability to expand the utility of QST toward its potential application in clinical settings and clinical predictive value. The aims of this study were to examine pain sensitivity using QST in adolescents with chronic pain compared to adolescents without chronic pain and identify predictors of pain sensitivity. A population-based study conducted from 2010 to 2011 provided data on 941 adolescents, 197 were classified as having chronic pain and 744 were classified without chronic pain. Self-reported data on pain characteristics, psychological functioning, and QST responses were examined. The findings revealed lower pressure pain threshold and tolerance on the trapezius (P's = 0.03) in adolescents with chronic pain compared to adolescents without chronic pain, but no differences on heat or cold-pressor pain tasks. Female sex (P's = 0.02) and poorer psychological functioning (P's = 0.02) emerged as significant predictors of greater pain sensitivity across all pain modalities. Exploratory analyses revealed several associations between clinical pain characteristics and QST responses within the chronic pain cohort. Findings from this large pediatric sample provide comprehensive data that could serve as normative data on QST responses in adolescents with and without chronic pain. These findings lay the groundwork toward developing future QST research and study protocols in pediatric populations, taking into consideration sex and psychological distress.

Indexed as

Chronic PainAdolescentAnalysis of VarianceAnthropometryCommunity Health PlanningFemaleHumansHyperalgesiaMaleNeurologic ExaminationPain MeasurementPain ThresholdPhysical StimulationRetrospective StudiesYoung Adult

Identifiers

PMID27780176
PMCPMC13585038

What OpenQuestion holds

Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.