Evidence map›Paper›PMID 27780077›Full record

ArticleCancer epidemiology2016

Association of cigarette smoking and microRNA expression in rectal cancer: Insight into tumor phenotype.

Lila E Mullany, Jennifer S Herrick, Roger K Wolff, John R Stevens, Martha L Slattery

Open access · hybridAbstract readComparative Study
In one paragraph

Article in Cancer epidemiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 52 citations in OpenAlex.

  1. Article
  2. Article
  3. miR-617 interacts with the promoter ofFrontiers in oncology · 2024
    Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
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  14. Article
  15. MiR-3150b inhibits hepatocellular carcinoma cell proliferation, migration and invasion by targeting GOLPH3.Journal of investigative medicine : the official publication of the American Federation for Clinical Research · 2020
    Article
  16. MiR-3150b-3p inhibits the progression of colorectal cancer cells via targeting GOLPH3.Journal of investigative medicine : the official publication of the American Federation for Clinical Research · 2020
    Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Lila E MullanyDepartment of Internal Medicine, University of Utah, 383 Colorow Bldg., Salt Lake City, UT 84108, USA. Electronic address: Lila.Mullany@hsc.utah.edu.
Jennifer S HerrickDepartment of Internal Medicine, University of Utah, 383 Colorow Bldg., Salt Lake City, UT 84108, USA. Electronic address: Jennifer.Herrick@hsc.utah.edu.
Roger K WolffDepartment of Internal Medicine, University of Utah, 383 Colorow Bldg., Salt Lake City, UT 84108, USA. Electronic address: Roger.Wolff@hsc.utah.edu.
John R StevensDepartment of Mathematics and Statistics, Utah State University, 3900 Old Main Hill, Logan, UT 84322, USA. Electronic address: john.r.stevens@usu.edu.
Martha L SlatteryDepartment of Internal Medicine, University of Utah, 383 Colorow Bldg., Salt Lake City, UT 84108, USA. Electronic address: Marty.Slattery@hsc.utah.edu.
University of Utah · USUtah State University · US

Funding

DIET, ACTIVITY &REPRODUCTION--RISKS FOR RECTAL CANCERR01CA048998 · NCI · UNIVERSITY OF UTAH · PI SLATTERY, MARTHA L · 1991 to 2012
$7.9M
miRNA and colorectal cancer: associations with tumor phenotype and survivalR01CA163683 · NCI · UNIVERSITY OF UTAH · PI SLATTERY, MARTHA L · 2012 to 2017
$6.5M
DIET, ACTIVITY &REPRODUCTION--RISKS FOR RECTAL CANCERU01CA048998 · NCI · UNIVERSITY OF UTAH · PI SLATTERY, MARTHA OR MARTY L · 1997 to 1999
–
NCI NIH HHS R01 CA048998NCI NIH HHS R01 CA163683NCI NIH HHS U01 CA048998
6 · The paper itself

Abstract

Smoking is known to influence messenger RNA (mRNA) expression in colorectal cancer (CRC) cases. As microRNAs (miRNAs) are known repressors of mRNAs, we hypothesize that smoking may influence miRNA expression, thus altering mRNA expression. Our sample consisted of 1447 CRC cases that had normal colorectal mucosa and carcinoma miRNA data and lifestyle data. We examined current smoking, current versus never and former versus never (C/F/N) smoking

Indexed as

Gene Expression Regulation, NeoplasticAdultAgedBiomarkers, TumorCase-Control StudiesFemaleGene Expression ProfilingHumansMaleMicroRNAsMiddle AgedPhenotypePrognosisRectal NeoplasmsRNA, MessengerSmokingBiomarkers, TumorMicroRNAsRNA, MessengerCIMPLife stylemicroRNAsMSINeoplasmsRectalSmoking

Identifiers

PMID27780077
PMCPMC5131860
OpenAlexW2538302144

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.