ArticleThe Journal of physiology2017
Distinct subcellular mechanisms for the enhancement of the surface membrane expression of SK2 channel by its interacting proteins, α-actinin2 and filamin A.
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Article in The Journal of physiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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19citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
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Who cites it
19 citing papers in PubMed, 22 citations in OpenAlex.
- A novel FLNA missense variant in a mother-daughter pair with epilepsy: case series evidence of variable multisystem expressivity.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026Article
- Intranasal Administration of KCNN2 Blocking Peptide Improves Deficits in Cognitive Flexibility in Mouse Model of Fetal Alcohol Spectrum Disorders.The international journal of neuropsychopharmacology · 2025Article
- Atomistic mechanisms of the regulation of small-conductance CaProceedings of the National Academy of Sciences of the United States of America · 2024Article
- Plasma membrane SK2 channel activity regulates migration and chemosensitivity of high-grade serous ovarian cancer cells.Molecular oncology · 2024Article
- From Atrial Small-conductance Calcium-activated Potassium Channels to New Antiarrhythmics.European cardiology · 2024Review
- In silico analysis of the dynamic regulation of cardiac electrophysiology by KThe Journal of physiology · 2023Article
- Small-conductance calcium-activated potassium channels in the heart: expression, regulation and pathological implications.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2023Review
- Enhanced CaCirculation research · 2023Article
- Differential Control of Small-conductance Calcium-activated Potassium Channel Diffusion by Actin in Different Neuronal Subcompartments.Function (Oxford, England) · 2023Article
- The regulation of the small-conductance calcium-activated potassium current and the mechanisms of sex dimorphism in J wave syndrome.Pflugers Archiv : European journal of physiology · 2021Review
- Different arrhythmia-associated calmodulin mutations have distinct effects on cardiac SK channel regulation.The Journal of general physiology · 2020Article
- PKA phosphorylation underlies functional recruitment of sarcolemmal SK2 channels in ventricular myocytes from hypertrophic hearts.The Journal of physiology · 2020Article
- Granule Cell Ensembles in Mouse Dentate Gyrus Rapidly Upregulate the Plasticity-Related Protein Synaptopodin after Exploration Behavior.Cerebral cortex (New York, N.Y. : 1991) · 2020Article
- Proceedings From the 2019 Stanford Single Ventricle Scientific Summit: Advancing Science for Single Ventricle Patients: From Discovery to Clinical Applications.Journal of the American Heart Association · 2020Article
- Rescue of tight junctional localization of a claudin-16 mutant D97S by antimalarial medicine primaquine in Madin-Darby canine kidney cells.Scientific reports · 2019Article
- Sex-specific activation of SK current by isoproterenol facilitates action potential triangulation and arrhythmogenesis in rabbit ventricles.The Journal of physiology · 2018Article
- Small-conductance CaExperimental & molecular medicine · 2018Review
- Coupling of SK channels, L-type CaScientific reports · 2018Article
- KThe Journal of physiology · 2017Article
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Authors and funding
13 authors at 4 institutions in 2 countries.
Zheng ZhangDivision of Cardiovascular Medicine, Department of Internal Medicine, University of California, Davis, CA, 95616, USA.
Hannah A LedfordDivision of Cardiovascular Medicine, Department of Internal Medicine, University of California, Davis, CA, 95616, USA.
Seojin ParkDivision of Cardiovascular Medicine, Department of Internal Medicine, University of California, Davis, CA, 95616, USA.
Wenying WangDepartment of Physiology and Cell Biology, University of Nevada, Reno, NV, 89557, USA.
Sassan RafizadehDivision of Cardiovascular Medicine, Department of Internal Medicine, University of California, Davis, CA, 95616, USA.
Hyo Jeong KimDivision of Cardiovascular Medicine, Department of Internal Medicine, University of California, Davis, CA, 95616, USA.
Wilson XuDivision of Cardiovascular Medicine, Department of Internal Medicine, University of California, Davis, CA, 95616, USA.
Ling LuDivision of Cardiovascular Medicine, Department of Internal Medicine, University of California, Davis, CA, 95616, USA.
Victor C LauDivision of Cardiovascular Medicine, Department of Internal Medicine, University of California, Davis, CA, 95616, USA.
Anne A KnowltonDivision of Cardiovascular Medicine, Department of Internal Medicine, University of California, Davis, CA, 95616, USA.
Xiao-Dong ZhangDivision of Cardiovascular Medicine, Department of Internal Medicine, University of California, Davis, CA, 95616, USA.
Ebenezer N YamoahDepartment of Physiology and Cell Biology, University of Nevada, Reno, NV, 89557, USA.
Nipavan ChiamvimonvatDivision of Cardiovascular Medicine, Department of Internal Medicine, University of California, Davis, CA, 95616, USA.ORCID 0000-0001-9499-8817
University of California, Davis · USUniversity of Nevada, Reno · USVA Northern California Health Care System · USNanjing Normal University · CN
Funding
Functional Interactions of Cardiac Ion ChannelsR01HL085844 · NHLBI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI CHIAMVIMONVAT, NIPAVAN · 2007 to 2025
$7.3MTraining Program In Basic & Translational Cardiovascular ScienceT32HL086350 · NHLBI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI Martin Cadeiras, David A. Liem · 2008 to 2026
$7.1MTranslational Study of Cardiac DysfunctionR01HL085727 · NHLBI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI CHIAMVIMONVAT, NIPAVAN, SIRISH, PADMINI · 2008 to 2022
$5.7MDecoding the enigma of cardiac amplificationR01HL137228 · NHLBI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI CHIAMVIMONVAT, NIPAVAN · 2017 to 2020
$2.2MRoles of K channels in spiral ganglia neurons in health, diseases and aging.R01DC010386 · NIDCD · UNIVERSITY OF NEVADA RENO · PI YAMOAH, EBENEZER N · 2010 to 2014
$1.9MFUNCTIONAL PROPERTIES OF CA PUMPS IN HAIR CELLR01DC004215 · NIDCD · UNIVERSITY OF CINCINNATI · PI YAMOAH, EBENEZER N. · 1999 to 2003
$1.0MIdentifying the receptors of environmentally sensitive epoxy-eicosanoids with AMSR00ES024806 · NIEHS · MICHIGAN STATE UNIVERSITY · PI LEE, KIN SING STEPHEN · 2017 to 2019
$727kIdentifying the Receptors of Environmentally Sensitive Epoxy-Eicosanoids with AMSK99ES024806 · NIEHS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI LEE, KIN SING STEPHEN · 2015 to 2016
$132kRegulation of ion channels in the heartI01BX000576 · VA · VA NORTHERN CALIFORNIA HEALTH CARE SYS · PI CHIAMVIMONVAT, NIPAVAN · 2009 to 2019
–Metabolomics study in patients post myocardial infarctionI01CX001490 · VA · VA NORTHERN CALIFORNIA HEALTH CARE SYS · PI CHIAMVIMONVAT, NIPAVAN · 2017 to 2021
–BLRD VA I01 BX000576CSRD VA I01 CX001490NHLBI NIH HHS R01 HL085727NHLBI NIH HHS R01 HL085844NHLBI NIH HHS R01 HL137228NHLBI NIH HHS T32 HL086350NIDCD NIH HHS R01 DC004215NIDCD NIH HHS R01 DC010386NIEHS NIH HHS K99 ES024806NIEHS NIH HHS R00 ES024806
Abstract
key pointsIon channels are transmembrane proteins that are synthesized within the cells but need to be trafficked to the cell membrane for the channels to function. Small-conductance, Ca ABSTRACT: The normal function of ion channels depends critically on the precise subcellular localization and the number of channel proteins on the cell surface membrane. Small-conductance, Ca
Indexed as
ActininAnimalsCell MembraneEndosomesFilaminsHeart AtriaHEK293 CellsHumansHydrazonesMaleMice, Inbred C57BLMyocytes, CardiacPrimaquineSmall-Conductance Calcium-Activated Potassium ChannelsActininACTN2 protein, humanFilaminsHydrazonesKCNN2 protein, humanN'-(3,4-dihydroxybenzylidene)-3-hydroxy-2-naphthahydrazidePrimaquineSmall-Conductance Calcium-Activated Potassium ChannelsAlpha-actinin2Ca-activated K channelFilamin AIon channel interacting proteinsRab GTPaseSK channels
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.