ReviewThe Journal of physiology2017
New perspectives on the development of muscle contractures following central motor lesions.
Review in The Journal of physiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
31 citing papers in PubMed.
- Acute Effects of Static and Proprioceptive Neuromuscular Facilitation Stretching of the Plantar Flexors on Ankle Range of Motion and Muscle-Tendon Behavior in Children with Spastic Cerebral Palsy-A Randomized Clinical Trial.International journal of environmental research and public health · 2022Trial
- Spasticity in Prolonged Disorders of Consciousness: A Prospective Cohort Study.Brain sciences · 2026Article
- Pain Unraveled: Kinesio Taping as a Novel Approach to Myofascial Pain Management.Current pain and headache reports · 2026Review
- Observational Evaluation of Muscle Echointensity and EMG Insertional Activity in Poststroke Spasticity.Muscle & nerve · 2026Observational
- Observational
- Feasibility, Safety, and Tolerability of Remote Ischemic Conditioning in Children with Unilateral Cerebral Palsy: A Randomized Controlled Trial.Children (Basel, Switzerland) · 2025Article
- Acute Postural Effects of Spinal Cord Injury: Dual Neural Opioid and Endocrine Non-Opioid Mechanism.Cells · 2025Article
- The correlation between lower limb spasticity and proprioceptive dysfunction in post-stroke patients.Frontiers in neurology · 2025Article
- Characterizing Muscle Tissue Quality Post-Stroke: Echovariation as a Clinical Indicator.Journal of clinical medicine · 2024Article
- Assessing muscle architecture with ultrasound: implications for spasticity.European journal of translational myology · 2024Article
- Focal Traumatic Brain Injury Impairs the Integrity of the Basement Membrane of Hindlimb Muscle Fibers Revealed by Extracellular Matrix Immunoreactivity.Life (Basel, Switzerland) · 2024Article
- Biomechanical testing of ex vivo porcine tendons following high intensity focused ultrasound thermal ablation.PloS one · 2024Article
- Passive mobilisation of the shoulder in subacute stroke patients with persistent arm paresis: A randomised multiple treatment trial.The South African journal of physiotherapy · 2022Article
- Brachial plexus birth injury and cerebral palsy lead to a common contracture phenotype characterized by reduced functional muscle length and strength.Frontiers in rehabilitation sciences · 2022Article
- How Can Biomechanics Improve Physical Preparation and Performance in Paralympic Athletes? A Narrative Review.Sports (Basel, Switzerland) · 2021Review
- Gene expressions in cerebral palsy subjects reveal structural and functional changes in the gastrocnemius muscle that are closely associated with passive muscle stiffness.Cell and tissue research · 2021Article
- Passive stiffness of fibrotic skeletal muscle in mdx mice relates to collagen architecture.The Journal of physiology · 2021Article
- The Contribution of Decreased Muscle Size to Muscle Weakness in Children With Spastic Cerebral Palsy.Frontiers in neurology · 2021Article
- Skeletal Muscle in Cerebral Palsy: From Belly to Myofibril.Frontiers in neurology · 2021Review
- Multi-frequency bioimpedance: a non-invasive tool for muscle-health assessment of adults with cerebral palsy.Journal of muscle research and cell motility · 2020Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Muscle contractures are common in patients with central motor lesions, but the mechanisms responsible for the development of contractures are still unclear. Increased or decreased neural activation, protracted placement of a joint with the muscle in a short position and muscle atrophy have been suggested to be involved, but none of these mechanisms are sufficient to explain the development of muscle contractures alone. Here we propose that changes in tissue homeostasis in the neuromuscular-tendon-connective tissue complex is at the heart of the development of contractures, and that an integrated physiological understanding of the interaction between neural, mechanical and metabolic factors, as well as genetic and epigenetic factors, is necessary in order to unravel the mechanisms that result in muscle contractures. We hope thereby to contribute to a reconsideration of how and why muscle contractures develop in a way which will open a window towards new insight in this area in the future.
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