Evidence map›Paper›PMID 27779362›Full record

ArticleVeterinary and comparative oncology2017

Role of monocyte recruitment in hemangiosarcoma metastasis in dogs.

D P Regan, A Escaffi, J Coy, J Kurihara, S W Dow

Abstract read
In one paragraph

Article in Veterinary and comparative oncology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.0field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
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  5. Review
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  10. Article
  11. Quantification of plasma cell-free DNA levels in dogs with various tumors.Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc · 2019
    Article
  12. Article
  13. Article
  14. Review
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

D P ReganFlint Animal Cancer Center, Department of Clinical Sciences, Colorado State University, Fort Collins, CO, USA.
A EscaffiFlint Animal Cancer Center, Department of Clinical Sciences, Colorado State University, Fort Collins, CO, USA.
J CoyFlint Animal Cancer Center, Department of Clinical Sciences, Colorado State University, Fort Collins, CO, USA.
J KuriharaFlint Animal Cancer Center, Department of Clinical Sciences, Colorado State University, Fort Collins, CO, USA.
S W DowFlint Animal Cancer Center, Department of Clinical Sciences, Colorado State University, Fort Collins, CO, USA.
Colorado State University · US

Funding

Biomedical Research Training for VeterinariansT32OD010437 · OD · COLORADO STATE UNIVERSITY · PI Gregg A Dean, KELLY S SANTANGELO · 2012 to 2026
$6.2M
Elucidating the role and regulation of periostin in therapy-induced chemoresistance in metastatic breast cancerK01OD022982 · OD · COLORADO STATE UNIVERSITY · PI REGAN, DANIEL PATRICK · 2016 to 2021
$720k
NIH HHS K01 OD022982NIH HHS T32 OD010437
6 · The paper itself

Abstract

Canine hemangiosarcoma (HSA) is a highly malignant tumour associated with short survival times because of early and widespread metastasis. In humans and rodents, monocytes play key roles in promoting tumour metastasis through stimulating tumour cell extravasation, seeding, growth and angiogenesis. Therefore, we investigated the potential association between monocyte infiltration and tumour metastasis in HSA and other common canine tumours. Immunohistochemistry was used to quantify CD18

Indexed as

AnimalsCD18 AntigensChemokine CCL2Dog DiseasesDogsFemaleFluorescent Antibody TechniqueHemangiosarcomaLung NeoplasmsMaleMonocytesCD18 AntigensChemokine CCL2cancerCCL2doghemangiosarcomametastasismonocytes

Identifiers

PMID27779362
PMCPMC6422335
OpenAlexW2540885541

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.