ArticleNature communications2016
Dynamic microfluidic control of supramolecular peptide self-assembly.
Article in Nature communications, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
33 citing papers in PubMed, 113 citations in OpenAlex.
- Formation of S- and Z-twist supramolecular micro-ropes by peptide stereoisomers.Nature communications · 2026Article
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- Effect of solvent-induced packing transitions on N-capped diphenylalanine peptide crystal growth.Nature communications · 2025Article
- Article
- Advanced Materials for Energy Harvesting and Soft Robotics: Emerging Frontiers to Enhance Piezoelectric Performance and Functionality.Advanced materials (Deerfield Beach, Fla.) · 2024Review
- Computational Fluid-Structure Interaction in Microfluidics.Micromachines · 2024Review
- Watching Molecular Nanotubes Self-Assemble in Real Time.Journal of the American Chemical Society · 2023Article
- Tuning Properties of Polyelectrolyte-Surfactant Associates in Two-Phase Microfluidic Flows.Polymers · 2022Article
- Natural Piezoelectric Biomaterials: A Biocompatible and Sustainable Building Block for Biomedical Devices.ACS nano · 2022Review
- On-Chip Control over Polyelectrolyte-Surfactant Complexation in Nonequilibrium Microfluidic Confinement.Polymers · 2022Article
- Antibody binding modulates the dynamics of the membrane-bound prion protein.Biophysical journal · 2022Article
- Dipeptide Nanostructure Assembly and DynamicsACS nano · 2021Article
- Synthesis, Characterization and Evaluation of Peptide Nanostructures for Biomedical Applications.Molecules (Basel, Switzerland) · 2021Review
- Sequence determinants of in cell condensate morphology, dynamics, and oligomerization as measured by number and brightness analysis.Cell communication and signaling : CCS · 2021Article
- Embedment of Quantum Dots and Biomolecules in a Dipeptide Hydrogel Formed In Situ Using Microfluidics.Angewandte Chemie (International ed. in English) · 2021Article
- Rapid highly sensitive general protein quantification through on-chip chemiluminescence.Biomicrofluidics · 2021Article
- A GSH/CB Dual-Controlled Self-Assembled Nanomedicine for High-Efficacy Doxorubicin-Resistant Breast Cancer Therapy.Frontiers in pharmacology · 2021Article
- Enabling Technology for Supramolecular Chemistry.Frontiers in chemistry · 2021Review
- Co-Assembly between Fmoc Diphenylalanine and Diphenylalanine within a 3D Fibrous Viscous Network Confers Atypical Curvature and Branching.Angewandte Chemie (International ed. in English) · 2020Article
- Interplay between structural hierarchy and exciton diffusion in artificial light harvesting.Nature communications · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 3 institutions in 3 countries.
Funding
Abstract
The dynamic nature of supramolecular polymers has a key role in their organization. Yet, the manipulation of their dimensions and polarity remains a challenge. Here, the minimalistic diphenylalanine building block was applied to demonstrate control of nano-assemblies growth and shrinkage using microfluidics. To fine-tune differential local environments, peptide nanotubes were confined by micron-scale pillars and subjected to monomer flows of various saturation levels to control assembly and disassembly. The small-volume device allows the rapid adjustment of conditions within the system. A simplified kinetic model was applied to calculate parameters of the growth mechanism. Direct real-time microscopy analysis revealed that different peptide derivatives show unidirectional or bidirectional axial dimension variation. Atomistic simulations show that unidirectional growth is dictated by the differences in the axial ends, as observed in the crystalline order of symmetry. This work lays foundations for the rational control of nano-materials dimensions for applications in biomedicine and material science.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.