Evidence map›Paper›PMID 27778153›Full record

ArticleTransgenic research2017

Phenotypic characterization of a novel HO-1 depletion model in the rat.

Vassilios Atsaves, Maria G Detsika, Elpida Poulaki, Hara Gakiopoulou, Elias A Lianos

Abstract read
PubMed Publisher
In one paragraph

Article in Transgenic research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.2field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Heme Oxygenase 1: A Defensive Mediator in Kidney Diseases.International journal of molecular sciences · 2021
    Review
  7. Review
  8. Review
  9. Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Vassilios Atsaves1st Division of Critical Care Medicine and Pulmonary Services, 'Evangelismos' Hospital, Department of Medicine, National and Kapodistrian University of Athens, School of Health Sciences, Athens, Greece.
Maria G Detsika1st Division of Critical Care Medicine and Pulmonary Services, 'Evangelismos' Hospital, Department of Medicine, National and Kapodistrian University of Athens, School of Health Sciences, Athens, Greece.
Elpida PoulakiDepartment of Pathology, National and Kapodistian University of Athens, School of Health Sciences, Athens, Greece.
Hara GakiopoulouDepartment of Pathology, National and Kapodistian University of Athens, School of Health Sciences, Athens, Greece.
Elias A Lianos1st Division of Critical Care Medicine and Pulmonary Services, 'Evangelismos' Hospital, Department of Medicine, National and Kapodistrian University of Athens, School of Health Sciences, Athens, Greece. ealianos2@gmail.com.
National and Kapodistrian University of Athens · GREvangelismos Hospital · GRRutgers Health

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although the protective role of HO-1 induction in various forms of kidney disease is well established, mechanisms other than heme catabolism to biliverdin, bilirubin and carbon monoxide have recently been identified. Unraveling these mechanisms requires the generation of appropriate animal models. The present study describes the generation of a HO-1 deficient Hmox1

Indexed as

Animalsbeta CateninCreatinineGene Knockout TechniquesHeme Oxygenase-1IronKidneyKidney DiseasesOxidative StressPodocytesRatsSpleenbeta CateninCreatinineHeme Oxygenase-1IronHeme oxygenase-1 (HO-1)KidneyRat model

Identifiers

PMID27778153
OpenAlexW2538118791

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.