ArticleJournal of industrial microbiology & biotechnology2016
Nitrogen deprivation of microalgae: effect on cell size, cell wall thickness, cell strength, and resistance to mechanical disruption.
Article in Journal of industrial microbiology & biotechnology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 133 citations in OpenAlex.
- Shape-Dependent Interactions of Gold Nanoparticles with Microalgae: Distinct Cellular and Molecular Responses.Environment & health (Washington, D.C.) · 2026Article
- From contamination to valorisation: a case study assessing culture contamination effect on the biofuel potential and nanomechanical properties of Parachlorella kessleri.Biotechnology for biofuels and bioproducts · 2026Article
- The GCN4-Swi6B module mediates low nitrogen-induced cell wall remodeling inApplied and environmental microbiology · 2025Article
- Adaptation to Long-Term Nitrogen Starvation in a Biocrust-Derived MicroalgaMicroorganisms · 2025Article
- Effects of nitrate limitation on the metabolome ofCurrent research in microbial sciences · 2025Article
- Neochloris oleoabundans cell wall rupture through melittin peptide: a new approach to increase lipid recovery.Biotechnology letters · 2024Article
- Structured population balances to support microalgae-based processes: Review of the state-of-art and perspectives analysis.Computational and structural biotechnology journal · 2023Review
- Sulfur Starvation in Extremophilic MicroalgaPlants (Basel, Switzerland) · 2022Article
- Effect of solid-state fermentation and ultrasonication processes on antimicrobial and antioxidant properties of algae extracts.Frontiers in nutrition · 2022Article
- Biphasic optimization approach for maximization of lipid production by the microalga Chlorella pyrenoidosa.Folia microbiologica · 2020Article
- Effects of Nitrogen Supplementation Status on COJournal of microbiology and biotechnology · 2020Article
- The Influence of Light and Nutrient Starvation on Morphology, Biomass and Lipid Content in Seven Strains of Green Microalgae as a Source of Biodiesel.Microorganisms · 2020Article
- Genetic Impairment of Cellulose Biosynthesis Increases Cell Wall Fragility and Improves Lipid Extractability from Oleaginous AlgaMicroorganisms · 2020Article
- Inhibition of TOR inCells · 2019Article
- The Detailed Comparison of Cell Death Detected by Annexin V-PI Counterstain Using Fluorescence Microscope, Flow Cytometry and Automated Cell Counter in Mammalian and Microalgae Cells.Journal of fluorescence · 2018Article
- A simple and inexpensive physical lysis method for DNA and RNA extraction from freshwater microalgae.3 Biotech · 2018Article
- A downstream box fusion allows stable accumulation of a bacterial cellulase inBiotechnology for biofuels · 2018Article
- Transcriptional Regulation of Cellulose Biosynthesis during the Early Phase of Nitrogen Deprivation in Nannochloropsis salina.Scientific reports · 2017Article
- Glycerolipid Characterization and Nutrient Deprivation-Associated Changes in the Green PicoalgaPlant physiology · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Nitrogen deprivation (N-deprivation) is a proven strategy for inducing triacylglyceride accumulation in microalgae. However, its effect on the physical properties of cells and subsequently on product recovery processes is relatively unknown. In this study, the effect of N-deprivation on the cell size, cell wall thickness, and mechanical strength of three microalgae was investigated. As determined by analysis of micrographs from transmission electron microscopy, the average cell size and cell wall thickness for N-deprived Nannochloropsis sp. and Chlorococcum sp. were ca. 25% greater than the N-replete cells, and 20 and 70% greater, respectively, for N-deprived Chlorella sp. The average Young's modulus of N-deprived Chlorococcum sp. cells was estimated using atomic force microscopy to be 775 kPa; 30% greater than the N-replete population. Although statistically significant, these microstructural changes did not appear to affect the overall susceptibility of cells to mechanical rupture by high pressure homogenisation. This is important as it suggests that subjecting these microalgae to nitrogen starvation to accumulate lipids does not adversely affect the recovery of intracellular lipids.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.