ReviewPediatric nephrology (Berlin, Germany)2017
Delayed graft function and its management in children.
Review in Pediatric nephrology (Berlin, Germany), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 29 citations in OpenAlex.
- Peri-transplant aminophylline in pediatric kidney transplant recipients of donation after brain death: a double-blinded placebo-controlled randomized clinical trial.Pediatric nephrology (Berlin, Germany) · 2020Trial
- Development and validation of a multidimensional machine learning model for predicting delayed graft function in deceased donor kidney transplantation.International urology and nephrology · 2026Article
- Prediction of delayed graft function after deceased donor kidney transplantation: development and temporal validation in a single-center cohort.BMC nephrology · 2026Article
- Risk Assessment of Delayed Graft Function in Pediatric Kidney Transplantation - a CERTAIN Research Network Analysis.Transplant international : official journal of the European Society for Organ Transplantation · 2026Article
- Hydrogen Sulfide in Experimental Organ Transplantation: From Bench to Bedside.Handbook of experimental pharmacology · 2026Review
- Outcomes of single kidney transplantation from small pediatric donors aged <5 years: comparative analysis between pediatric and adult recipients.Renal failure · 2025Article
- Haemodynamic effect of dexmedetomidine during paediatric kidney transplantation.Pediatric nephrology (Berlin, Germany) · 2025Article
- An integrated machine learning model enhances delayed graft function prediction in pediatric renal transplantation from deceased donors.BMC medicine · 2024Article
- Pediatric renal transplantation; 10 years experience.Turkish journal of surgery · 2021Article
- Pretransplant Serum Uromodulin and Its Association with Delayed Graft Function Following Kidney Transplantation-A Prospective Cohort Study.Journal of clinical medicine · 2021Article
- Protection of the transplant kidney during cold perfusion with doxycycline: proteomic analysis in a rat model.Proteome science · 2020Article
- Angiotensin II Type 1 receptor antibodies are associated with inflammatory cytokines and poor clinical outcomes in pediatric kidney transplantation.Kidney international · 2018Observational
- Eculizumab in Renal Transplantation: A 2017 Update.Annals of transplantation · 2017Review
- Outcomes for primary kidney transplantation from donation after Citizens' death in China: a single center experience of 367 cases.BMC health services research · 2017Article
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Delayed graft function (DGF) is commonly defined as the requirement for dialysis within the first 7 days following renal transplantation. The major underlying mechanism is related to ischaemia/reperfusion injury, which includes microvascular inflammation and cell death and apoptosis, and to the regeneration processes. Several clinical factors related to donor, recipient and organ procurement/transplantation procedures may increase the risk of DGF, including donor cardiovascular instability, older donor age, donor creatinine concentration, long cold ischaemia time and marked body mass index of both the donor and recipient. Some of these parameters have been used in specific predictive formulas created to assess the risk of DGF. A variety of other pre-, intra- and post-transplant clinical factors may also increase the risk of DGF, such as potential drug nephrotoxicity, surgical problems and/or hyperimmunization of the recipient. DGF may decrease the long-term graft function, but data on this effect are inconsistent, partially due to the many different types of organ donation. Relevant management strategies may be classified into the classic clinical approach, which has the aim of minimizing the individual risk factors of DGF, and specific pharmacologic strategies, which are designed to prevent or treat ischaemia/reperfusion injury. Both strategies are currently being evaluated in clinical trials.
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