ArticleHeart and vessels2017
Association between the body mass index and the clinical findings in patients with acute heart failure: evaluation of the obesity paradox in patients with severely decompensated acute heart failure.
Article in Heart and vessels, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Nutrition in chronic heart failure patients: a systematic review.Heart failure reviews · 2020Pooled it
- Association between body mass index and clinical outcomes in patients with acute myocardial infarction and reduced systolic function: Analysis of PARADISE-MI trial data.European journal of heart failure · 2025Trial
- The creatinine-to-body weight ratio predicts mortality in critically ill patients with heart failure: a retrospective cohort study of the MIMIC-IV database.BMC cardiovascular disorders · 2026Article
- Poor cardiovascular outcomes of underweight abdominal obesity in the entire population of newly diagnosed heart failure.ESC heart failure · 2025Article
- Association of the Serpine1 with the Obesity Paradox in Ischemic Heart Failure.Iranian journal of public health · 2025Article
- The impact of geriatric nutritional risk index on one-year outcomes in hospitalized elderly patients with heart failure.Frontiers in cardiovascular medicine · 2023Article
- Sarcopenic obesity is associated with impaired physical function and mortality in older patients with heart failure: insight from FRAGILE-HF.BMC geriatrics · 2022Article
- Construction of a risk assessment model of cardiovascular disease in a rural Chinese hypertensive population based on lasso-Cox analysis.Journal of clinical hypertension (Greenwich, Conn.) · 2022Article
- The Relationship Between Body Mass Index and In-hospital Survival in Patients Admitted With Acute Heart Failure.Frontiers in cardiovascular medicine · 2022Article
- Obesity paradox and heart failure.Eating and weight disorders : EWD · 2021Review
- Article
- Malnutrition and Frailty Are Critical Determinants of 6-Month Outcome in Hospitalized Elderly Patients With Heart Failure Harboring Surgically Untreated Functional Mitral Regurgitation.Frontiers in cardiovascular medicine · 2021Article
- Association between body mass index and prognosis of patients hospitalized with heart failure.Scientific reports · 2020Article
- The controlling nutritional status score predicts outcomes of cardiovascular events in patients with heart failure with preserved ejection fraction.International journal of cardiology. Heart & vasculature · 2020Article
- Prognostic Value of Both Plasma Volume Status and Nutritional Status in Patients With Severely Decompensated Acute Heart Failure.CJC open · 2019Article
- Gender Differences in the Social Determinants of the Long-term Prognosis for Severely Decompensated Acute Heart Failure in Patients over 75 Years of Age.Internal medicine (Tokyo, Japan) · 2019Article
- Impact of Body Mass Index on Activities of Daily Living in Inpatients with Acute Heart Failure.The journal of nutrition, health & aging · 2019Article
- The prognostic impact of malnutrition in patients with severely decompensated acute heart failure, as assessed using the Prognostic Nutritional Index (PNI) and Controlling Nutritional Status (CONUT) score.Heart and vessels · 2018Article
- Significance of sequential cardiac rehabilitation program through inter-hospital cooperation between acute care and rehabilitation hospitals in elderly patients after cardiac surgery in Japan.Heart and vessels · 2017Article
Corrections and comments
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Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Obesity is known to be associated with the development of heart failure (HF). However, the relationship between the body mass index (BMI) and acute HF (AHF) remains to be elucidated. Eight hundred and eight AHF patients were enrolled in this study. The patients were assigned to four groups according to their BMI values: severely thin (n = 11, BMI <16), normal/underweight (n = 579, 16 ≤ BMI <25), overweight (n = 178, 25 ≤ BMI <30) and obese (n = 40, BMI ≥30). The patients in the severely thin group were more likely to be female, have systolic blood pressure (SBP) <100 mmHg and have valvular disease than normal/underweight patients. The patients in the overweight group were significantly younger than those in the normal/underweight, and those in the overweight group were more likely to have SBP ≥140 mmHg and hypertensive heart disease and less likely to have valvular disease than the patients in the normal/underweight group. The prognosis, including all-cause death, was significantly poorer among patients who were severely thin than those who were normal/underweight, overweight and significantly better among those who were overweight than those who were normal/underweight, severely thin and obese patients. A multivariate Cox regression model identified that severely thin [HR: 3.372, 95% confidence interval (CI) 1.362-8.351] and overweight (HR: 0.615, 95% CI 0.391-0.966) were independent predictors of 910-day mortality as the reference of normal/underweight. Overweight patients tended to have SBP ≥140 mmHg and be relatively young, while severely thin patients tended to have SBP <100 mmHg and be female. These factors were associated with a better prognosis of overweight patients and adverse outcomes in severely thin patients. These factors may contribute to the "obesity paradox" in severely decompensated AHF patients.
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