Evidence map›Paper›PMID 27777975›Full record

ArticleJCI insight2016

The role for neutrophil extracellular traps in cystic fibrosis autoimmunity.

Sladjana Skopelja, B JoNell Hamilton, Jonathan D Jones, Mei-Ling Yang, Mark Mamula, Alix Ashare, Alex H Gifford, William Fc Rigby

Open access · goldAbstract read
In one paragraph

Article in JCI insight, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed, 1 pooled it
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 1 synthesis or guideline pooled it, 74 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. A crucial role of neutrophil extracellular traps in pulmonary infectious diseases.Chinese medical journal pulmonary and critical care medicine · 2024
    Review
  5. HowInternational journal of molecular sciences · 2023
    Review
  6. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Sladjana SkopeljaDepartment of Microbiology and Immunology and.
B JoNell HamiltonDepartment of Microbiology and Immunology and.
Jonathan D JonesDivision of Rheumatology, Department of Medicine, Geisel School of Medicine at Dartmouth, Lebanon, New Hampshire, USA.
Mei-Ling YangSection of Rheumatology, Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut, USA.
Mark MamulaSection of Rheumatology, Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut, USA.
Alix AshareDepartment of Microbiology and Immunology and.
Alex H GiffordDivision of Pulmonology, Department of Medicine, Geisel School of Medicine at Dartmouth, Lebanon, New Hampshire, USA.
William Fc RigbyDepartment of Microbiology and Immunology and.
Dartmouth College · USDartmouth Psychiatric Research Center · USYale University · US

Funding

Translational Engineering in Cancer (TEC)P30CA023108 · NCI · DARTMOUTH COLLEGE · PI Steven D Leach · 1985 to 2026
$91.3M
TRANSLATIONAL RESEARCH COREP30GM106394 · NIGMS · DARTMOUTH COLLEGE · PI MADDEN, DEAN R · 2013 to 2017
$6.1M
Regional Hypoxia Impacts the Heterogeneity of Inflammatory Lung DiseaseR01HL122372 · NHLBI · DARTMOUTH-HITCHCOCK CLINIC · PI ASHARE, ALIX · 2015 to 2019
$2.0M
NCI NIH HHS P30 CA023108NHLBI NIH HHS R01 HL122372NIGMS NIH HHS P30 GM106394
6 · The paper itself

Abstract

While respiratory failure in cystic fibrosis (CF) frequently associates with chronic infection by

Indexed as

AutoimmunityAdolescentAdultAnti-Citrullinated Protein AntibodiesAntimicrobial Cationic PeptidesArthritis, RheumatoidBlood ProteinsCross ReactionsCystic FibrosisExtracellular TrapsFemaleHumansMaleMembrane ProteinsMiddle AgedPseudomonas aeruginosaAnti-Citrullinated Protein AntibodiesAntimicrobial Cationic Peptidesbactericidal permeability increasing proteinBlood ProteinsMembrane Proteins

Identifiers

PMID27777975
PMCPMC5070963
OpenAlexW2536907359

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.