Evidence map›Paper›PMID 27777837›Full record

ArticleChemistryOpen2016

Synthesis of Functional Fluorescent BODIPY-based Dyes through Electrophilic Aromatic Substitution: Straightforward Approach towards Customized Fluorescent Probes.

Giorgio Mirri, Daniël C Schoenmakers, Paul H J Kouwer, Peter Veranič, Igor Muševič, Bogdan Štefane

Abstract read
In one paragraph

Article in ChemistryOpen, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Giorgio MirriCondensed Matter Physics Department Jožef Stefan Institute Jamova 39 1000 Ljubljana Slovenia; Institute for Molecules and Materials Radboud University Nijmegen Heyendaalseweg 135 6525 AJ Nijmegen The Netherlands.ORCID 0000-0001-8960-3614
Daniël C SchoenmakersInstitute for Molecules and Materials Radboud University Nijmegen Heyendaalseweg 135 6525 AJ Nijmegen The Netherlands.
Paul H J KouwerInstitute for Molecules and Materials Radboud University Nijmegen Heyendaalseweg 135 6525 AJ Nijmegen The Netherlands.
Peter VeraničInstitute of Cell Biology Faculty of Medicine University of Ljubljana Vrazov trg 2 1000 Ljubljana Slovenia.
Igor MuševičCondensed Matter Physics Department Jožef Stefan Institute Jamova 39 1000 Ljubljana Slovenia.
Bogdan ŠtefaneOrganic Chemistry Department Faculty of Chemistry and Chemical Technology University of Ljubljana Večna pot 113 1000 Ljubljana Slovenia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fluorescent materials are widely used in biological and material applications as probes for imaging or sensing; however, their customization is usually complicated without the support of an organic chemistry laboratory. Here, we present a straightforward method for the customization of BODIPY cores, which are among the most commonly used fluorescent probes. The method is based on the formation of a new C-C bond through Friedel-Crafts electrophilic aromatic substitution carried out at room temperature. The method presented can be used to obtain completely customized fluorescent materials in one or two steps from commercially available compounds. Examples of the preparation of fluorescent materials for cell staining and functionalization of silica colloids are also presented.

Indexed as

BODIPYcell stainingdyes/pigmentselectrophilic aromatic substitutionfluorescent colloids

Identifiers

PMID27777837
PMCPMC5062010

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.