Evidence map›Paper›PMID 27777591›Full record

ArticleAllergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology2016

Interacting effects of obesity, race, ethnicity and sex on the incidence and control of adult-onset asthma.

Corinna Koebnick, Heidi Fischer, Matthew F Daley, Assiamira Ferrara, Michael A Horberg, Beth Waitzfelder, Deborah Rohm Young, Michael K Gould

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Article
  6. Association of Obesity and Severe Asthma in Adults.Journal of clinical medicine · 2024
    Review
  7. Article
  8. Review
  9. Article
  10. Asthma interactions between obesity and other risk factors.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2022
    Review
  11. Article
  12. Obesity increases airway smooth muscle responses to contractile agonists.American journal of physiology. Lung cellular and molecular physiology · 2018
    Article
  13. Unequal Gain of Equal Resources across Racial Groups.International journal of health policy and management · 2018
    Article
  14. Vitamin D3 levels and NLRP3 expression in murine models of obese asthma: association with asthma outcomes.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2017
    Article
  15. Prevalence of interstitial and other lung diseases on Aruba.Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Corinna KoebnickDepartment of Research and Evaluation, Kaiser Permanente Southern California, 100 S. Los Robles, 2nd Floor, Pasadena, CA 91101 USA.
Heidi FischerDepartment of Research and Evaluation, Kaiser Permanente Southern California, 100 S. Los Robles, 2nd Floor, Pasadena, CA 91101 USA.
Matthew F DaleyInstitute for Health Research, Kaiser Permanente Colorado, 10065 E. Harvard Street Suite 300, Denver, CO 80231 USA.
Assiamira FerraraDivision of Research, Kaiser Permanente Northern California, 2000 Broadway, Oakland, CA 94612 USA.
Michael A HorbergMid-Atlantic Permanente Research Institute, Kaiser Permanente Mid-Atlantic States, 2101 East Jefferson Street 3 West, Rockville, MD 20852 USA.
Beth WaitzfelderCenter for Health Research-Hawaii, Kaiser Permanente Hawaii, 501 Alakawa Street Suite 201, Honolulu, HI 96817 USA.
Deborah Rohm YoungDepartment of Research and Evaluation, Kaiser Permanente Southern California, 100 S. Los Robles, 2nd Floor, Pasadena, CA 91101 USA.
Michael K GouldDepartment of Research and Evaluation, Kaiser Permanente Southern California, 100 S. Los Robles, 2nd Floor, Pasadena, CA 91101 USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo improve care and control for patients with adult-onset asthma, a better understanding of determinants of their risk and outcomes is important. We investigated how associations between asthma, asthma control and obesity may be modified by patient demographic characteristics.

methodsThis retrospective study of adults enrolled in several health plans across the U.S. (n = 2,860,305) examined the interacting effects of obesity, age, race, and sex on adult-onset asthma and asthma control. Multivariable adjusted Cox and logistic regression models estimated hazard ratios (HR), and 95 % confidence intervals (CI) for the associations between body mass index (BMI) and study outcomes, and interactions of BMI with demographic characteristics.

resultsCompared with individuals who had a BMI <25 kg/m

conclusionsThe present study demonstrates that the magnitude of the associations between obesity and adult-onset asthma incidence and control are modified by race, age, and sex. Understanding the role of obesity in the development of adult-onset asthma will help to improve asthma treatment algorithms and to develop targeted interventions.

Indexed as

Adult-onsetAsthmaEthnicityObesityRaceSex

Identifiers

PMID27777591
PMCPMC5069790

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.