Evidence map›Paper›PMID 27777513›Full record

ArticleProteome science2016

Multi-omics analysis on the pathogenicity of

Dijun Zhang, Weina He, Qianqian Tong, Jun Zhou, Xiurong Su

Abstract read
In one paragraph

Article in Proteome science, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Comparison ofFrontiers in microbiology · 2023
    Article
  3. Immunopathological Changes Post-Infection withArchives of Razi Institute · 2022
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Dijun ZhangSchool of Marine Science, Ningbo University, 818 Fenghua Road, Ningbo, Zhejiang Province 315211 People's Republic of China.
Weina HeSchool of Marine Science, Ningbo University, 818 Fenghua Road, Ningbo, Zhejiang Province 315211 People's Republic of China.
Qianqian TongSchool of Marine Science, Ningbo University, 818 Fenghua Road, Ningbo, Zhejiang Province 315211 People's Republic of China.
Jun ZhouSchool of Marine Science, Ningbo University, 818 Fenghua Road, Ningbo, Zhejiang Province 315211 People's Republic of China.
Xiurong SuSchool of Marine Science, Ningbo University, 818 Fenghua Road, Ningbo, Zhejiang Province 315211 People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe acquisition of iron is important for the pathogenicity of bacteria and blood. Three different culture environments (Fe stimulation, blood agar plate and normal plate) were used to stimulate

methods2D-DIGE combined with MALDI-TOF-MS/MS, RT-PCR and

resultsA total of 109 proteins were identified by 2D-DIGE and mass spectrometry after pairwise comparison within three culture environments, clustered into 3 classes and 183 functional categories, which were involved in 23 pathways. Based on the 2D-DIGE results, multiple proteins were selected for verification by mRNA expression. These results confirmed that most of the proteins were regulated at the transcriptional level. Thirty-eight metabolites were detected by NMR, which correlated with the differentially expressed proteins under different treatment conditions.

conclusionsThe results show that culture in a blood agar plate and a suitable concentration of iron promote the pathogenicity of

Indexed as

Enterobacter cloacaeIronMetabolomicPathogenicityProteomic

Identifiers

PMID27777513
PMCPMC5070189

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.