Evidence map›Paper›PMID 27777502›Full record

ArticleMolecular vision2016

Analysis of

Linda M Reis, Rebecca C Tyler, Eric Weh, Kathryn E Hendee, Ariana Kariminejad, Omar Abdul-Rahman, Tawfeg Ben-Omran, Melanie A Manning, Ahmet Yesilyurt, Catherine A McCarty and 3 more

Open access · greenAbstract read
In one paragraph

Article in Molecular vision, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
0.3field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Genetic Analysis ofBiomedicines · 2025
    Article
  5. Insights intoLife (Basel, Switzerland) · 2025
    Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Review
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 3 countries.

Linda M ReisDepartment of Pediatrics and Children's Research Institute at the Medical College of Wisconsin and Children's Hospital of Wisconsin, Milwaukee, WI.
Rebecca C TylerDepartment of Pediatrics and Children's Research Institute at the Medical College of Wisconsin and Children's Hospital of Wisconsin, Milwaukee, WI.
Eric WehDepartment of Pediatrics and Children's Research Institute at the Medical College of Wisconsin and Children's Hospital of Wisconsin, Milwaukee, WI.
Kathryn E HendeeDepartment of Pediatrics and Children's Research Institute at the Medical College of Wisconsin and Children's Hospital of Wisconsin, Milwaukee, WI; Department of Cell Biology, Neurobiology and Anatomy, Medical College of Wisconsin, Milwaukee, WI.
Ariana KariminejadKariminejad-Najmabadi Pathology and Genetics Center, Tehran, Iran.
Omar Abdul-RahmanDepartment of Pediatrics, University of Mississippi Medical Center, Jackson, MS.
Tawfeg Ben-OmranClinical and Metabolic Genetics, Department of Pediatrics, Hamad Medical Corporation and Weill Cornell Medical College, Doha-Qatar.
Melanie A ManningDivision of Medical Genetics, Department of Pathology and Department of Pediatrics, Stanford University School of Medicine, Stanford, CA.
Ahmet YesilyurtDiskapi Yildirim Beyazit Training and Education Hospital, Genetic Diagnosis Center, Ankara, Turkey
Catherine A McCartyMarshfield Clinic Research Foundation, Center for Human Genetics Department, Marshfield WI.
Terrie E KitchnerMarshfield Clinic Research Foundation, Center for Human Genetics Department, Marshfield WI.
Deborah CostakosDepartment of Ophthalmology, Medical College of Wisconsin, Milwaukee, WI.
Elena V SeminaDepartment of Pediatrics and Children's Research Institute at the Medical College of Wisconsin and Children's Hospital of Wisconsin, Milwaukee, WI; Department of Cell Biology, Neurobiology and Anatomy, Medical College of Wisconsin, Milwaukee, WI; Department of Ophthalmology, Medical College of Wisconsin, Milwaukee, WI.
Dışkapı Yıldırım Beyazıt Eğitim ve Araştırma Hastanesi · TRMedical College of Wisconsin · USUniversity of Mississippi Medical Center · USWeill Cornell Medical College in Qatar · QA

Funding

Institutional Clinical and Translational Science AwardUL1TR000427 · NCATS · UNIVERSITY OF WISCONSIN-MADISON · PI DREZNER, MARC KENNETH · 2012 to 2016
$32.2M
MORPHOLOGY MODULEP30EY001931 · NEI · MEDICAL COLLEGE OF WISCONSIN · PI BURKE, JANICE M. · 1985 to 2016
$9.8M
CTSA INFRASTRUCTURE FOR PEDIATRIC RESEARCHUL1RR031973 · NCRR · MEDICAL COLLEGE OF WISCONSIN · PI SHAKER, REZA NONE · 2010 to 2011
$7.9M
Molecular Mechanisms of Axenfeld-Rieger SyndromeR01EY015518 · NEI · MEDICAL COLLEGE OF WISCONSIN · PI Elena V Semina · 2005 to 2026
$5.6M
Rresearch Training Program in Vision ScienceT32EY014537 · NEI · MEDICAL COLLEGE OF WISCONSIN · PI Elena V Semina · 2002 to 2026
$4.2M
NCATS NIH HHS UL1 TR000427NCRR NIH HHS UL1 RR031973NEI NIH HHS P30 EY001931NEI NIH HHS R01 EY015518NEI NIH HHS T32 EY014537
6 · The paper itself

Abstract

purposeThe

methodsWe examined

resultsRecessive pathogenic variants in

conclusionsIn summary, these data expand the mutational and phenotypic spectra of

Indexed as

MutationAdultAgedAged, 80 and overAllelesAnterior Eye SegmentChildChild, PreschoolCytochrome P-450 CYP1B1DNA Mutational AnalysisFemaleGlaucoma, Open-AngleHumansHydrophthalmosMaleMiddle AgedCYP1B1 protein, humanCytochrome P-450 CYP1B1

Identifiers

PMID27777502
PMCPMC5070572
OpenAlexW2539646020

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.