Evidence map›Paper›PMID 27777420›Full record

ArticleMolecular psychiatry2018

Blockade of the K

S Moriguchi, T Ishizuka, Y Yabuki, N Shioda, Y Sasaki, H Tagashira, H Yawo, J Z Yeh, H Sakagami, T Narahashi and 1 more

Abstract read
PubMed Publisher
In one paragraph

Article in Molecular psychiatry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
2.7field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 50 citations in OpenAlex.

  1. Review
  2. Review
  3. Parkinson's disease and glucose metabolism impairment.Translational neurodegeneration · 2025
    Review
  4. Article
  5. Article
  6. The role of the adenylate kinase 5 gene in various diseases and cancer.Journal of clinical and translational science · 2024
    Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Functional Regulation of KFrontiers in pharmacology · 2022
    Review
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

S MoriguchiDepartment of Pharmacology, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Japan.
T IshizukaDepartment of Developmental Biology and Neuroscience, Graduate School of Life Sciences, Tohoku University, Sendai, Japan.
Y YabukiDepartment of Pharmacology, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Japan.
N ShiodaDepartment of Pharmacology, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Japan.
Y SasakiDepartment of Pharmacology, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Japan.
H TagashiraDepartment of Pharmacology, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Japan.
H YawoDepartment of Developmental Biology and Neuroscience, Graduate School of Life Sciences, Tohoku University, Sendai, Japan.
J Z YehDepartment of Molecular Pharmacology and Biological Chemistry, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
H SakagamiDepartment of Anatomy, Kitasato University School of Medicine, Sagamihara, Japan.
T NarahashiDepartment of Molecular Pharmacology and Biological Chemistry, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
K FukunagaDepartment of Pharmacology, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Japan.
Tohoku University · JPNorthwestern University · USKitasato University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Here, we report a novel target of the drug memantine, ATP-sensitive K

Indexed as

Alzheimer DiseaseAnimalsCalcium-Calmodulin-Dependent Protein Kinase Type 2DendritesDisease Models, AnimalHippocampusHumansKcnj11 ChannelLong-Term PotentiationMemantineMemoryMemory DisordersMiceMice, TransgenicNeuronsPhosphorylationCalcium-Calmodulin-Dependent Protein Kinase Type 2Kcnj11 ChannelMemantinemitochondrial K(ATP) channelPotassium ChannelsPotassium Channels, Inwardly Rectifying

Identifiers

PMID27777420
OpenAlexW2537716058

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.