ArticleJournal of lipid research2016
Increasing insulin resistance accentuates the effect of triglyceride-associated loci on serum triglycerides during 5 years.
Article in Journal of lipid research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Effect of a 12-week bungy pump training on cardiorespiratory fitness, metabolic syndrome factors and body composition in postmenopausal women.Scientific reports · 2025Article
- An 8-week ketogenic diet improves exercise endurance and liver antioxidant capacity after weight loss in obese mice.Frontiers in nutrition · 2023Article
- Type 2 Diabetes Risk and Lipid Metabolism Related to the Pleiotropic Effects of anMetabolites · 2022Article
- The correlation of atherosclerosis and triglyceride glucose index: a secondary analysis of a national cross-sectional study of Japanese.BMC cardiovascular disorders · 2022Article
- Causal relationships between lipid and glycemic levels in an Indian population: A bidirectional Mendelian randomization approach.PloS one · 2020Article
Corrections and comments
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Authors and funding
10 authors.
Funding
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Abstract
Blood concentrations of triglycerides are influenced by genetic factors as well as a number of environmental factors, including adiposity and glucose homeostasis. The aim was to investigate the association between a serum triglyceride weighted genetic risk score (wGRS) and changes in fasting serum triglyceride level over 5 years and to test whether the effect of the wGRS was modified by 5 year changes of adiposity, insulin resistance, and lifestyle factors. A total of 3,474 nondiabetic individuals from the Danish Inter99 cohort participated in both the baseline and 5 year follow-up physical examinations and had information on the wGRS comprising 39 genetic variants. In a linear regression model adjusted for age, sex, and baseline serum triglyceride, the wGRS was associated with increased serum triglyceride levels over 5 years [per allele effect = 1.3% (1.0-1.6%); P = 1.0 × 10
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