Who was studied, and how
Three numbers in the abstract
Where each one falls
Only readable comparisons vote
Where it lands on the map
What it changes
Among 8 other studies
people with hypertension, in this paper
The trial randomly assignedassigned by chance
Exenatide-infusion
placebo
Reported higher RHR, no range given+7.50
randomisedThe trial randomly assignedassigned by chance
liraglutide
placebo
Reported higher RHR, no range given+6.60
Reported lower systolic BP, no range given−12.6
randomisedthe abstract, start to end
… increased RHR (mean ± s.e.m. +7.5 ± 0.9 BPM, P < 0.001), and …
… with liraglutide increased RHR (+6.6 ± 2.1 BPM), while reducing systolic BP (-12.6 ± 4.7 mmHg) and stroke volume …
← favours treatmentfavours comparator →
could be chanceNo interval given · direction only, strength unknown
RHRExenatide-infusion vs placebo
7.5
RHRliraglutide vs placebo
6.6
Systolic BPliraglutide vs placebo
−12.6
GLP-1 receptor agonistsBody weight & compositionBlood pressureCardiac & vascular function
GLP-1 receptor agonists × blood pressurehelps?mixed
unlikelylikely
0.500.17 without it
GLP-1 receptor agonists × body weight & compositionhelps?replicated
unlikelylikely
0.910.92 without it
← favours treatmentfavours comparator →
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