ArticleMayo Clinic proceedings2016
Kidney Function After the First Kidney Stone Event.
Article in Mayo Clinic proceedings, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.
- Systematic review of the risk of urolithiasis following parathyroidectomy in patients with primary hyperparathyroidism.International urology and nephrology · 2024Pooled it
- Balancing Stone Prevention and Kidney Function: A Therapeutic Dilemma.Journal of clinical medicine · 2025Review
- MDCT-based Grading of Perirenal Changes Secondary to Acute Unilateral Upper Urinary Tract Obstruction.Current medical imaging · 2025Article
- Association between Kidney Stones and CKD: A Bidirectional Mendelian Randomization Study.Journal of the American Society of Nephrology : JASN · 2024Article
- Association between body roundness index and prevalence of kidney stone in the U.S: a study based on the NHANES database.BMC urology · 2024Article
- Association between DCP levels and kidney stone prevalence in US female adults based on NHANES data.Scientific reports · 2024Article
- Risk of incident chronic kidney disease among patients with urolithiasis: a nationwide longitudinal cohort study.Clinical kidney journal · 2024Article
- Recurrent nephrolithiasis and loss of kidney function: a cohort study.International urology and nephrology · 2023Article
- Incidence of and risk factors of chronic kidney disease: results of a nationwide study in Iceland.Clinical kidney journal · 2022Article
- A retrospective study on sex difference in patients with urolithiasis: who is more vulnerable to chronic kidney disease?Biology of sex differences · 2021Article
- Trends in the prevalence of kidney stones in the United States from 2007 to 2016.Urolithiasis · 2021Article
- Evaluation of inactive Matrix-Gla-Protein (MGP) as a biomarker for incident and recurrent kidney stones.Journal of nephrology · 2020Article
- Association of sirtuin 1 gene polymorphisms with nephrolithiasis in Eastern chinese population.Renal failure · 2019Article
- Risk of ESRD and Mortality in Kidney and Bladder Stone Formers.American journal of kidney diseases : the official journal of the National Kidney Foundation · 2018Article
- Uric acid stones increase the risk of chronic kidney disease.Urolithiasis · 2018Article
- Article
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
Abstract
objectiveTo determine whether there is a persistent decline in kidney function after the first kidney stone event. PATIENT AND
methodsIncident symptomatic stone formers and age- and sex-matched controls underwent 2 study visits 90 days apart to assess kidney function, complete a survey, and have their medical records reviewed. Kidney function was compared between stone formers and controls adjusting for clinical, blood, and urine risk factors.
resultsThere were 384 stone formers and 457 controls. At visit 1, a median of 104 days after the stone event, stone formers compared with controls had similar serum creatinine (0.86 vs 0.84 mg/dL; P=.23), higher serum cystatin C (0.83 vs 0.72 mg/L; P<.001), higher urine protein (34.2 vs 19.7 mg/24 h; P<.001) levels, and were more likely to have albuminuria (24 h urine albumin >30 mg: 5.4% vs 2.2%; P=.02). Findings were similar after adjustment for risk factors and at visit 2, a median of 92 days after visit 1. In the 173 stone formers with serum creatinine levels from care before study participation, the mean serum creatinine level was 0.84 mg/dL before the stone event, increased to 0.97 mg/dL (P<.001) at the stone event, but returned to 0.85 mg/dL (P=.38) after the stone event (visit 1).
conclusionsIncident symptomatic stone formers have a rise in serum creatinine levels that resolves. However, stone formers have sustained higher cystatin C levels and proteinuria that may affect long-term risk of chronic kidney disease.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.