Evidence map›Paper›PMID 27776670›Full record

ReviewEuropean journal of radiology2016

Quantitative computed tomography measurements to evaluate airway disease in chronic obstructive pulmonary disease: Relationship to physiological measurements, clinical index and visual assessment of airway disease.

Atsushi Nambu, Jordan Zach, Joyce Schroeder, Gongyoung Jin, Song Soo Kim, Yu-Il Kim, Christina Schnell, Russell Bowler, David A Lynch

Open access · greenAbstract readReview
In one paragraph

Review in European journal of radiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed, 1 pooled it
6.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

55 citing papers in PubMed, 1 synthesis or guideline pooled it, 92 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. COPD: pulmonary vascular volume associated with cardiac structure and function.The international journal of cardiovascular imaging · 2024
    Article
  9. Article
  10. Article
  11. Correlation Between HIF1-A Expression and Airway Remodeling in COPD.International journal of chronic obstructive pulmonary disease · 2024
    Article
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  13. Observational
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  15. Review
  16. Article
  17. Review
  18. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Atsushi NambuDepartment of Radiology, National Jewish Health, 1400 Jackson Street, Denver, CO, 80206, USA. Electronic address: nambu-a@gray.plala.or.jp.
Jordan ZachDepartment of Radiology, National Jewish Health, 1400 Jackson Street, Denver, CO, 80206, USA. Electronic address: ZachJ@NJHealth.org.
Joyce SchroederDepartment of Radiology, National Jewish Health, 1400 Jackson Street, Denver, CO, 80206, USA. Electronic address: Joyce.schroeder@stanfordalumni.org.
Gongyoung JinDepartment of Radiology, National Jewish Health, 1400 Jackson Street, Denver, CO, 80206, USA. Electronic address: gyjin@chonbuk.ac.kr.
Song Soo KimDepartment of Radiology, National Jewish Health, 1400 Jackson Street, Denver, CO, 80206, USA. Electronic address: haneul88@hanmail.net.
Yu-Il KimDepartment of Medicine, National Jewish Health, Denver, CO, USA. Electronic address: kyionly@chonnam.ac.kr.
Christina SchnellDepartment of Medicine, National Jewish Health, Denver, CO, USA. Electronic address: SchnellC@NJHealth.org.
Russell BowlerDivision of Pulmonary Medicine, Department of Medicine, National Jewish Health, USA. Electronic address: BowlerR@NJHealth.org.
David A LynchDepartment of Radiology, National Jewish Health, 1400 Jackson Street, Denver, CO, 80206, USA. Electronic address: LynchD@NJHealth.org.
National Jewish Health · USUniversity of Colorado Denver · US

Funding

Genetic Epidemiology of COPDU01HL089897 · NHLBI · NATIONAL JEWISH HEALTH · PI CRAPO, JAMES D · 2007 to 2021
$56.9M
Metabolomic signatures of empysema and COPD progression in the COPDGene cohortR01HL089897 · NHLBI · NATIONAL JEWISH HEALTH · PI CRAPO, JAMES D · 2012 to 2016
$31.1M
Genetic Epidemiology of COPDU01HL089856 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI SILVERMAN, EDWIN K · 2007 to 2021
$20.7M
(2 of 2) Genetic Epidemiology of COPDR01HL089856 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI SILVERMAN, EDWIN K · 2012 to 2016
$18.9M
Ultra-low Dose, High Speed, High Resolution, Multispectral, Multi-Source MDCT ScaS10OD018526 · OD · UNIVERSITY OF IOWA · PI HOFFMAN, ERIC ALFRED · 2015 to 2015
$2.0M
NHLBI NIH HHS R01 HL089856NHLBI NIH HHS R01 HL089897NHLBI NIH HHS U01 HL089856NHLBI NIH HHS U01 HL089897NIH HHS S10 OD018526
6 · The paper itself

Abstract

purposeTo correlate currently available quantitative CT measurements for airway disease with physiological indices and the body-mass index, airflow obstruction, dyspnea, and exercise capacity (BODE) index in patients with chronic obstructive pulmonary disease (COPD). MATERIALS AND

methodsThis study was approved by our institutional review board (IRB number 2778). Written informed consent was obtained from all subjects. The subjects included 188 current and former cigarette smokers from the COPDGene cohort who underwent inspiratory and expiratory CT and also had physiological measurements for the evaluation of airflow limitation, including FEF25-75%, airway resistance (Raw), and specific airway conductance (sGaw). The BODE index was used as the index of clinical symptoms. Quantitative CT measures included % low attenuation areas [% voxels≤950 Hounsfield unit (HU) on inspiratory CT, %LAA

resultsQuantitative CT measurements had significant correlations with physiological indices. Among them, E/I-ratio

conclusionQuantitative CT measurements of gas trapping such as E/I-ratio

Indexed as

Tomography, X-Ray ComputedAgedBody Mass IndexDyspneaFemaleForced Expiratory VolumeHumansLungMaleMiddle AgedPulmonary Disease, Chronic ObstructivePulmonary EmphysemaRadiographic Image Interpretation, Computer-AssistedRetrospective StudiesSeverity of Illness IndexSmokingAir trappingAirway diseaseChronic obstructive lung disease (COPD)CTQuantitative CT

Identifiers

PMID27776670
PMCPMC5310933
OpenAlexW2519434758

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.