ArticleInternational journal of health geographics2016
Optimal health and disease management using spatial uncertainty: a geographic characterization of emergent artemisinin-resistant Plasmodium falciparum distributions in Southeast Asia.
Article in International journal of health geographics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.
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Who cites it
12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 18 citations in OpenAlex.
- Spatio-temporal trends of the prevalence of Plasmodium falciparum antimalarial drug resistance markers across sub-Saharan Africa from 2010 to 2024: a systematic review and meta-analysis.BMC infectious diseases · 2026Pooled it
- Systematic Review and Geospatial Modeling of Molecular Markers of Resistance to Artemisinins and Sulfadoxine-Pyrimethamine in Plasmodium falciparum in India.The American journal of tropical medicine and hygiene · 2024Pooled it
- Model-guided geospatial surveillance system for antimalarial drug resistance.PLOS global public health · 2026Article
- A multi-criteria framework for disease surveillance site selection: case study forRoyal Society open science · 2024Article
- A spatio-temporal model of multi-marker antimalarial resistance.Journal of the Royal Society, Interface · 2024Article
- Spatiotemporal spread of Plasmodium falciparum mutations for resistance to sulfadoxine-pyrimethamine across Africa, 1990-2020.PLoS computational biology · 2022Article
- Mapping partner drug resistance to guide antimalarial combination therapy policies in sub-Saharan Africa.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- On the emergence, spread and resistance ofJournal of medical microbiology · 2021Review
- Characterizing local-scale heterogeneity of malaria risk: a case study in Bunkpurugu-Yunyoo district in northern Ghana.Malaria journal · 2019Article
- Tagging to endogenous genes of Plasmodium falciparum using CRISPR/Cas9.Parasites & vectors · 2017Article
- malERA: An updated research agenda for combination interventions and modelling in malaria elimination and eradication.PLoS medicine · 2017Review
- The threat of artemisinin resistant malaria in Southeast Asia.Travel medicine and infectious diseaseArticle
Corrections and comments
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Authors and funding
34 authors at 14 institutions in 11 countries.
Funding
Abstract
backgroundArtemisinin-resistant Plasmodium falciparum malaria parasites are now present across much of mainland Southeast Asia, where ongoing surveys are measuring and mapping their spatial distribution. These efforts require substantial resources. Here we propose a generic 'smart surveillance' methodology to identify optimal candidate sites for future sampling and thus map the distribution of artemisinin resistance most efficiently.
methodsThe approach uses the 'uncertainty' map generated iteratively by a geostatistical model to determine optimal locations for subsequent sampling.
resultsThe methodology is illustrated using recent data on the prevalence of the K13-propeller polymorphism (a genetic marker of artemisinin resistance) in the Greater Mekong Subregion.
conclusionThis methodology, which has broader application to geostatistical mapping in general, could improve the quality and efficiency of drug resistance mapping and thereby guide practical operations to eliminate malaria in affected areas.
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