ArticlePloS one2016
The MADS Box Genes ABS, SHP1, and SHP2 Are Essential for the Coordination of Cell Divisions in Ovule and Seed Coat Development and for Endosperm Formation in Arabidopsis thaliana.
Article in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.
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44 citing papers in PubMed, 75 citations in OpenAlex.
- ARABIDOPSIS Bsister and SEEDSTICK MADS-box transcription factors modulate maternal nutrient flow for seed development in Arabidopsis.Nature communications · 2026Article
- Post-polyploid chromosomal diploidization in plants is affected by clade divergence and constrained by shared genomic features.Nature communications · 2026Article
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- AnPlants (Basel, Switzerland) · 2025Article
- Insights into genetics of floral development in Amborella trichopoda Baill. through genome-wide survey and expression analysis of MADS-Box transcription factors.Scientific reports · 2025Article
- Natural variations inProceedings of the National Academy of Sciences of the United States of America · 2025Article
- Genome-wide characterization of the MADS-box gene family in Paeonia ostii and expression analysis of genes related to floral organ development.BMC genomics · 2025Article
- Constitutive expression of full-length or partial ofFrontiers in plant science · 2025Article
- Single-nucleus RNA and ATAC sequencing analyses provide molecular insights into early pod development of peanut fruit.Plant communications · 2024Article
- Genome-wide analysis of MADS-box genes and their expression patterns in unisexual flower development in dioecious spinach.Scientific reports · 2024Article
- An Overview on MADS Box Members in Plants: A Meta-Review.International journal of molecular sciences · 2024Review
- The maternal embrace: the protection of plant embryos.Journal of experimental botany · 2024Review
- Seed shape and size ofFrontiers in plant science · 2024Article
- Article
- AGPs as molecular determinants of reproductive development.Annals of botany · 2023Article
- MADS-Box Subfamily GeneInternational journal of molecular sciences · 2023Article
- Maternal control of triploid seed development by the TRANSPARENT TESTA 8 (TT8) transcription factor in Arabidopsis thaliana.Scientific reports · 2023Article
- Comparative transcriptome analysis identifies candidate genes related to seed coat color in rapeseed.Frontiers in plant science · 2023Article
- Exploiting plant transcriptomic databases: Resources, tools, and approaches.Plant communications · 2022Review
- Genome-Wide Analysis of the MADS-Box Gene Family in Holoparasitic Plants (Frontiers in plant science · 2022Article
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6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Seed formation is a pivotal process in plant reproduction and dispersal. It begins with megagametophyte development in the ovule, followed by fertilization and subsequently coordinated development of embryo, endosperm, and maternal seed coat. Two closely related MADS-box genes, SHATTERPROOF 1 and 2 (SHP1 and SHP2) are involved in specifying ovule integument identity in Arabidopsis thaliana. The MADS box gene ARABIDOPSIS BSISTER (ABS or TT16) is required, together with SEEDSTICK (STK) for the formation of endothelium, part of the seed coat and innermost tissue layer formed by the maternal plant. Little is known about the genetic interaction of SHP1 and SHP2 with ABS and the coordination of endosperm and seed coat development. In this work, mutant and expression analysis shed light on this aspect of concerted development. Triple tt16 shp1 shp2 mutants produce malformed seedlings, seed coat formation defects, fewer seeds, and mucilage reduction. While shp1 shp2 mutants fail to coordinate the timely development of ovules, tt16 mutants show less peripheral endosperm after fertilization. Failure in coordinated division of the innermost integument layer in early ovule stages leads to inner seed coat defects in tt16 and tt16 shp1 shp2 triple mutant seeds. An antagonistic action of ABS and SHP1/SHP2 is observed in inner seed coat layer formation. Expression analysis also indicates that ABS represses SHP1, SHP2, and FRUITFUL expression. Our work shows that the evolutionary conserved Bsister genes are required not only for endothelium but also for endosperm development and genetically interact with SHP1 and SHP2 in a partially antagonistic manner.
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