Evidence map›Paper›PMID 27775721›Full record

ArticleNature neuroscience2016

The brain adapts to dishonesty.

Neil Garrett, Stephanie C Lazzaro, Dan Ariely, Tali Sharot

Abstract read
In one paragraph

Article in Nature neuroscience, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed
9.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 171 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Article
  4. The Amygdala and Politics.Brain sciences · 2026
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Creative thinking does not promote dishonesty.Royal Society open science · 2023
    Article
  16. Article
  17. Cognitive load promotes honesty.Psychological research · 2023
    Article
  18. Review
  19. Model Sharing in the Human Medial Temporal Lobe.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022
    Article
  20. Decision neuroscience and neuroeconomics: Recent progress and ongoing challenges.Wiley interdisciplinary reviews. Cognitive science · 2022
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Neil GarrettAffective Brain Lab, Department of Experimental Psychology, University College London, London, UK.
Stephanie C LazzaroAffective Brain Lab, Department of Experimental Psychology, University College London, London, UK.
Dan ArielyFuqua School of Business, Duke University, Durham, North Carolina, USA.
Tali SharotAffective Brain Lab, Department of Experimental Psychology, University College London, London, UK.
University College London · GBDuke University · US

Funding

Wellcome Trust 093807
6 · The paper itself

Abstract

Dishonesty is an integral part of our social world, influencing domains ranging from finance and politics to personal relationships. Anecdotally, digressions from a moral code are often described as a series of small breaches that grow over time. Here we provide empirical evidence for a gradual escalation of self-serving dishonesty and reveal a neural mechanism supporting it. Behaviorally, we show that the extent to which participants engage in self-serving dishonesty increases with repetition. Using functional MRI, we show that signal reduction in the amygdala is sensitive to the history of dishonest behavior, consistent with adaptation. Critically, the extent of reduced amygdala sensitivity to dishonesty on a present decision relative to the previous one predicts the magnitude of escalation of self-serving dishonesty on the next decision. The findings uncover a biological mechanism that supports a 'slippery slope': what begins as small acts of dishonesty can escalate into larger transgressions.

Indexed as

MoralsAdaptation, BiologicalAdolescentAdultAgedBehaviorBrainDecision MakingFemaleHumansMagnetic Resonance ImagingMaleMiddle AgedYoung Adult

Identifiers

PMID27775721
PMCPMC5238933
OpenAlexW2538748553

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.