ReviewInternational journal of molecular sciences2016
Critical Analysis of the Melanogenic Pathway in Insects and Higher Animals.
Review in International journal of molecular sciences, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 96 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
96 citing papers in PubMed, 222 citations in OpenAlex.
- miR-34 regulates cuticle pigmentation by targetingRNA biology · 2026Article
- Article
- Is the developmental stage important for the plasticity of transgenerational immune priming?Biology open · 2026Article
- Camptothecin weakens the mechanical properties of insect cuticle by inhibiting tanning.Insect science · 2026Article
- Gene Expression and Structural Differences Underpinning Black and White Colouration in Spiders.Molecular ecology · 2026Article
- Regulatory mechanisms of nutritional factors on melanin deposition in Taihe Silky Fowls: review.Animal bioscience · 2026Article
- 6-Methoxyluteolin from the Invasive PlantInsects · 2026Article
- Genomics and reproductive biology of Leptopilina malgretoutensis (sp. nov.): an asexual parasitoid of Caribbean Drosophila.Genetics · 2026Article
- Convergent evolution of albinism in cave animals is driven by shared mechanisms and adaptive advantages.Communications biology · 2026Article
- Melanin-Inspired Biomimetic Strategy for Preserving Adhesion of Lubricants via Thiol-Quinone Addition.Biomimetics (Basel, Switzerland) · 2026Article
- A Simple Method for Estimating the Spatiotemporal Distribution of Phenoloxidase Proteins in Insect Tissues.Bio-protocol · 2026Article
- The Genetic Basis of Color Polymorphism in the Orb-Web SpiderEcology and evolution · 2026Article
- Fabrication and Functional Modification Strategies of Squid Ink-Derived Nanoparticles: From Natural Melanin to Multifunctional Biomaterials.Marine drugs · 2026Review
- The Redox Properties of Polyphenols and Their Role in ROS Generation for Biomedical Applications.Angewandte Chemie (International ed. in English) · 2026Review
- Article
- Skin Whitening Creams: Cosmetovigilance.Current pharmaceutical biotechnology · 2026Review
- Article
- Melanin biosynthesis and functional roles in insects: insights into immunological defense, physiological regulation, and environmental adaptation.Annals of medicine and surgery (2012) · 2025Review
- The Combination of Pterocarpus marsupium Bark Extract, Pinus strobus Bark Extract, and Ascorbyl Tetraisopalmitate Inhibits Melanogenesis via Nicotinamide Nucleotide Transhydrogenase Activation.Journal of cosmetic dermatology · 2025Article
- Chemical Profile and Biological Data of Alphitobius diaperinus Panzer, 1797 (Coleoptera: Tenebrionidae) Using Gas Chromatography-Mass Spectrometry and Image Analysis.Neotropical entomology · 2025Article
36 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Animals synthesize melanin pigments for the coloration of their skin and use it for their protection from harmful solar radiation. Insects use melanins even more ingeniously than mammals and employ them for exoskeletal pigmentation, cuticular hardening, wound healing and innate immune responses. In this review, we discuss the biochemistry of melanogenesis process occurring in higher animals and insects. A special attention is given to number of aspects that are not previously brought to light: (1) the molecular mechanism of dopachrome conversion that leads to the production of two different dihydroxyindoles; (2) the role of catecholamine derivatives other than dopa in melanin production in animals; (3) the critical parts played by various biosynthetic enzymes associated with insect melanogenesis; and (4) the presence of a number of important gaps in both melanogenic and sclerotinogenic pathways. Additionally, importance of the melanogenic process in insect physiology especially in the sclerotization of their exoskeleton, wound healing reactions and innate immune responses is highlighted. The comparative biochemistry of melanization with sclerotization is also discussed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.