Evidence map›Paper›PMID 27775592›Full record

ArticleInternational journal of molecular sciences2016

Prokaryotic Expression, Purification and Immunogenicity in Rabbits of the Small Antigen of Hepatitis Delta Virus.

Vera L Tunitskaya, Olesja V Eliseeva, Vladimir T Valuev-Elliston, Daria A Tyurina, Natalia F Zakirova, Olga A Khomich, Martins Kalis, Oleg E Latyshev, Elizaveta S Starodubova, Olga N Ivanova and 3 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.2field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 2 countries.

Vera L TunitskayaEngelhardt Institute of Molecular Biology, Russian Academy of Sciences, Vavilov str. 32, Moscow 119991, Russia. ve_tun@mail.ru.
Olesja V EliseevaGamaleya Research Center of Epidemiology and Microbiology, Gamaleja str. 16, Moscow 123098, Russia. olesenka80@mail.ru.
Vladimir T Valuev-EllistonEngelhardt Institute of Molecular Biology, Russian Academy of Sciences, Vavilov str. 32, Moscow 119991, Russia. gansfaust@mail.ru.
Daria A TyurinaEngelhardt Institute of Molecular Biology, Russian Academy of Sciences, Vavilov str. 32, Moscow 119991, Russia. tyurina.dascha@gmail.com.
Natalia F ZakirovaEngelhardt Institute of Molecular Biology, Russian Academy of Sciences, Vavilov str. 32, Moscow 119991, Russia. nat_zakirova@mail.ru.
Olga A KhomichEngelhardt Institute of Molecular Biology, Russian Academy of Sciences, Vavilov str. 32, Moscow 119991, Russia. o.a.khomich@gmail.com.
Martins KalisA Kirchenstein Institute of Microbiology and Virology, Research Department, Riga Stradins University, Dzirciema iela 16, Riga LV-1007, Latvia. martins.kalis@rsu.lv.
Oleg E LatyshevGamaleya Research Center of Epidemiology and Microbiology, Gamaleja str. 16, Moscow 123098, Russia. oleglat80@mail.ru.
Elizaveta S StarodubovaEngelhardt Institute of Molecular Biology, Russian Academy of Sciences, Vavilov str. 32, Moscow 119991, Russia. estarodubova@yandex.ru.
Olga N IvanovaEngelhardt Institute of Molecular Biology, Russian Academy of Sciences, Vavilov str. 32, Moscow 119991, Russia. olgaum@yandex.ru.
Sergey N KochetkovEngelhardt Institute of Molecular Biology, Russian Academy of Sciences, Vavilov str. 32, Moscow 119991, Russia. kochet@eimb.ru.
Maria G IsaguliantsGamaleya Research Center of Epidemiology and Microbiology, Gamaleja str. 16, Moscow 123098, Russia. maria.issagouliantis@rsu.lv.
Alexander V IvanovEngelhardt Institute of Molecular Biology, Russian Academy of Sciences, Vavilov str. 32, Moscow 119991, Russia. aivanov@yandex.ru.
Engelhardt Institute of Molecular Biology · RUGamalei Institute of Epidemiology and Microbiology · RURiga Stradiņš University · LV

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatitis delta virus (HDV) is a viroid-like blood-borne human pathogen that accompanies hepatitis B virus infection in 5% patients. HDV has been studied for four decades; however, the knowledge on its life-cycle and pathogenesis is still sparse. The studies are hampered by the absence of the commercially-available HDV-specific antibodies. Here, we describe a set of reproducible methods for the expression in

Indexed as

AnimalsAntibodies, ViralCell LineCloning, MolecularEnzyme-Linked Immunosorbent AssayEscherichia coliFemaleFluorescent Antibody TechniqueHepatitis delta AntigensHepatitis Delta VirusHumansRabbitsRecombinant ProteinsRNA, ViralAntibodies, ViralHepatitis delta AntigensRecombinant ProteinsRNA, Viralhepatitis delta virusprokaryotic expressionprotein purificationrabbit immunization

Identifiers

PMID27775592
PMCPMC5085752
OpenAlexW2536895748

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.